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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & CRWrnafold [.zip] - may take several seconds...


Overview

Metric MXScarna(20) CRWrnafold
MCC 0.569 > 0.546
Average MCC ± 95% Confidence Intervals 0.543 ± 0.221 < 0.574 ± 0.189
Sensitivity 0.466 < 0.483
Positive Predictive Value 0.701 > 0.623
Total TP 110 < 114
Total TN 32655 > 32629
Total FP 68 < 81
Total FP CONTRA 6 < 10
Total FP INCONS 41 < 59
Total FP COMP 21 > 12
Total FN 126 > 122
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(20) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and CRWrnafold).

  2. Comparison of performance of MXScarna(20) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and CRWrnafold).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and CRWrnafold).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and CRWrnafold).

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Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 110
Total TN 32655
Total FP 68
Total FP CONTRA 6
Total FP INCONS 41
Total FP COMP 21
Total FN 126
Total Scores
MCC 0.569
Average MCC ± 95% Confidence Intervals 0.543 ± 0.221
Sensitivity 0.466
Positive Predictive Value 0.701
Nr of predictions 7

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.86 0.74 1.00 20 2983 2 0 0 2 7
3SD1_A 0.63 0.55 0.74 23 3885 8 2 6 0 19
4A1C_3 0.64 0.56 0.75 30 7100 11 2 8 1 24
4A1C_2 0.18 0.15 0.21 5 11757 36 2 17 17 28
4AOB_A 0.62 0.55 0.72 23 4339 10 0 9 1 19
4ENB_A 0.26 0.11 0.67 2 1272 1 0 1 0 17
4ENC_A 0.60 0.37 1.00 7 1319 0 0 0 0 12

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 114
Total TN 32629
Total FP 81
Total FP CONTRA 10
Total FP INCONS 59
Total FP COMP 12
Total FN 122
Total Scores
MCC 0.546
Average MCC ± 95% Confidence Intervals 0.574 ± 0.189
Sensitivity 0.483
Positive Predictive Value 0.623
Nr of predictions 7

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.67 0.59 0.76 16 2982 7 0 5 2 11
3SD1_A 0.52 0.45 0.61 19 3885 12 2 10 0 23
4A1C_3 0.70 0.59 0.84 32 7102 6 0 6 0 22
4A1C_2 0.13 0.15 0.13 5 11741 44 4 31 9 28
4AOB_A 0.59 0.48 0.74 20 4344 8 2 5 1 22
4ENB_A 0.70 0.58 0.85 11 1262 2 1 1 0 8
4ENC_A 0.70 0.58 0.85 11 1313 2 1 1 0 8

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.