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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(seed) - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(seed) & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric MXScarna(seed) Multilign(seed)
MCC 0.560 > 0.558
Average MCC ± 95% Confidence Intervals 0.526 ± 0.209 < 0.538 ± 0.265
Sensitivity 0.448 > 0.434
Positive Predictive Value 0.707 < 0.725
Total TP 128 > 124
Total TN 36947 < 36957
Total FP 67 > 49
Total FP CONTRA 5 < 6
Total FP INCONS 48 > 41
Total FP COMP 14 > 2
Total FN 158 < 162
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(seed) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(seed) and Multilign(seed)).

  2. Comparison of performance of MXScarna(seed) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(seed) and Multilign(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(seed) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(seed) and Multilign(seed)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(seed) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(seed) and Multilign(seed)).

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Performance of MXScarna(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(seed)

Total Base Pair Counts
Total TP 128
Total TN 36947
Total FP 67
Total FP CONTRA 5
Total FP INCONS 48
Total FP COMP 14
Total FN 158
Total Scores
MCC 0.560
Average MCC ± 95% Confidence Intervals 0.526 ± 0.209
Sensitivity 0.448
Positive Predictive Value 0.707
Nr of predictions 8

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2. Individual counts for MXScarna(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.57 0.55 0.61 11 972 7 0 7 0 9
2LC8_A -0.01 0.00 0.00 0 1530 12 0 10 2 20
3RKF_A 0.72 0.53 1.00 18 2193 0 0 0 0 16
3SD1_A 0.63 0.55 0.74 23 3885 8 1 7 0 19
3W3S_B 0.69 0.60 0.80 24 4723 6 0 6 0 16
3ZEX_C 0.32 0.19 0.53 10 14177 20 2 7 11 42
4AOB_A 0.66 0.55 0.79 23 4342 7 0 6 1 19
4FRN_A 0.62 0.53 0.73 19 5125 7 2 5 0 17

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Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 124
Total TN 36957
Total FP 49
Total FP CONTRA 6
Total FP INCONS 41
Total FP COMP 2
Total FN 162
Total Scores
MCC 0.558
Average MCC ± 95% Confidence Intervals 0.538 ± 0.265
Sensitivity 0.434
Positive Predictive Value 0.725
Nr of predictions 8

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.85 1.00 17 973 0 0 0 0 3
2LC8_A -0.01 0.00 0.00 0 1528 12 1 11 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.55 0.45 0.68 19 3888 9 1 8 0 23
3W3S_B 0.84 0.73 0.97 29 4723 2 0 1 1 11
3ZEX_C 0.39 0.27 0.58 14 14172 10 3 7 0 38
4AOB_A 0.61 0.45 0.83 19 4348 5 0 4 1 23
4FRN_A 0.24 0.17 0.35 6 5134 11 1 10 0 30

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.