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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Mastr(20) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Mastr(20) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric Mastr(20) CMfinder(20)
MCC 0.575 > 0.546
Average MCC ± 95% Confidence Intervals 0.494 ± 0.635 < 0.560 ± 0.222
Sensitivity 0.421 > 0.366
Positive Predictive Value 0.793 < 0.822
Total TP 69 > 60
Total TN 21145 < 21159
Total FP 21 > 15
Total FP CONTRA 1 = 1
Total FP INCONS 17 > 12
Total FP COMP 3 > 2
Total FN 95 < 104
P-value 0.0

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Performance plots


  1. Comparison of performance of Mastr(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Mastr(20) and CMfinder(20)).

  2. Comparison of performance of Mastr(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Mastr(20) and CMfinder(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Mastr(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Mastr(20) and CMfinder(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for Mastr(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Mastr(20) and CMfinder(20)).

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Performance of Mastr(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 69
Total TN 21145
Total FP 21
Total FP CONTRA 1
Total FP INCONS 17
Total FP COMP 3
Total FN 95
Total Scores
MCC 0.575
Average MCC ± 95% Confidence Intervals 0.494 ± 0.635
Sensitivity 0.421
Positive Predictive Value 0.793
Nr of predictions 4

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.70 1.00 21 2829 1 0 0 1 9
3J2L_3 0.34 0.25 0.48 13 7848 16 1 13 2 40
3ZEX_D 0.80 0.71 0.90 35 6982 4 0 4 0 14
4FRG_B 0.00 0.00 0.00 0 3486 0 0 0 0 32

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 60
Total TN 21159
Total FP 15
Total FP CONTRA 1
Total FP INCONS 12
Total FP COMP 2
Total FN 104
Total Scores
MCC 0.546
Average MCC ± 95% Confidence Intervals 0.560 ± 0.222
Sensitivity 0.366
Positive Predictive Value 0.822
Nr of predictions 4

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.75 0.57 1.00 17 2833 1 0 0 1 13
3J2L_3 0.45 0.32 0.63 17 7848 11 1 9 1 36
3ZEX_D 0.58 0.39 0.86 19 6999 3 0 3 0 30
4FRG_B 0.47 0.22 1.00 7 3479 0 0 0 0 25

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.