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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Mastr(20) - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Mastr(20) & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric Mastr(20) Mastr(seed)
MCC 0.514 > 0.000
Average MCC ± 95% Confidence Intervals 0.492 ± 0.109 > 0.000 ± 0.000
Sensitivity 0.339 > 0.000
Positive Predictive Value 0.784 > 0.000
Total TP 443 > 0
Total TN 247895 < 248460
Total FP 155 > 0
Total FP CONTRA 15 > 0
Total FP INCONS 107 > 0
Total FP COMP 33 > 0
Total FN 862 < 1305
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of Mastr(20) and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Mastr(20) and Mastr(seed)).

  2. Comparison of performance of Mastr(20) and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Mastr(20) and Mastr(seed)).

  3. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Mastr(20) and Mastr(seed)).

  4. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Mastr(20) and Mastr(seed)).

  5. Comparison of average Matthews Correlation Coefficients (MCCs) for Mastr(20) and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Mastr(20) and Mastr(seed)).

  6. Comparison of average Matthews Correlation Coefficients (MCCs) for Mastr(20) and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Mastr(20) and Mastr(seed)).

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Performance of Mastr(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 443
Total TN 247895
Total FP 155
Total FP CONTRA 15
Total FP INCONS 107
Total FP COMP 33
Total FN 862
Total Scores
MCC 0.514
Average MCC ± 95% Confidence Intervals 0.492 ± 0.109
Sensitivity 0.339
Positive Predictive Value 0.784
Nr of predictions 34

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2L94_A 0.87 0.80 0.94 16 973 1 0 1 0 4
2WRQ_Y 0.57 0.59 0.56 10 2832 12 5 3 4 7
2XKV_B 0.45 0.20 1.00 4 4556 3 0 0 3 16
2XQD_Y 0.88 0.78 1.00 21 2829 0 0 0 0 6
2XXA_G 0.41 0.17 1.00 7 5144 0 0 0 0 35
3A2K_C 0.72 0.61 0.85 17 2906 3 0 3 0 11
3AMU_B 0.77 0.59 1.00 16 2987 1 0 0 1 11
3G4S_9 0.48 0.32 0.75 18 7357 8 1 5 2 39
3GX2_A 0.39 0.28 0.55 11 4351 10 0 9 1 29
3IVN_B 0.78 0.65 0.95 20 2325 1 1 0 0 11
3IZ4_A 0.00 0.00 0.00 0 70876 0 0 0 0 132
3IZF_C 0.73 0.63 0.85 34 6863 7 1 5 1 20
3J20_0 0.84 0.70 1.00 21 2829 1 0 0 1 9
3J20_1 0.25 0.22 0.29 5 2909 12 0 12 0 18
3J2L_3 0.34 0.25 0.48 13 7848 16 1 13 2 40
3JYV_7 0.81 0.66 1.00 21 2829 0 0 0 0 11
3JYX_4 0.00 0.00 0.00 0 12246 0 0 0 0 33
3JYX_3 0.56 0.56 0.58 15 6302 23 1 10 12 12
3LA5_A 0.76 0.59 1.00 20 2465 0 0 0 0 14
3NPB_A 0.30 0.24 0.39 11 6993 18 1 16 1 35
3O58_2 0.76 0.76 0.76 29 7222 12 3 6 3 9
3O58_3 0.00 0.00 0.00 0 12403 0 0 0 0 35
3PDR_A 0.00 0.00 0.00 0 12880 0 0 0 0 72
3RKF_A 0.70 0.50 1.00 17 2194 0 0 0 0 17
3SD1_A 0.61 0.50 0.75 21 3888 7 1 6 0 21
3ZEX_C 0.00 0.00 0.00 0 14196 0 0 0 0 52
3ZEX_D 0.80 0.71 0.90 35 6982 4 0 4 0 14
4A1C_3 0.70 0.59 0.84 32 7102 7 0 6 1 22
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.39 0.26 0.58 11 4352 9 0 8 1 31
4ENB_A 0.39 0.16 1.00 3 1272 0 0 0 0 16
4ENC_A 0.51 0.26 1.00 5 1321 0 0 0 0 14
4FRG_B 0.00 0.00 0.00 0 3486 0 0 0 0 32

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 248460
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 1305
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 34

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.00 0.00 0.00 0 406 0 0 0 0 11
2L94_A 0.00 0.00 0.00 0 990 0 0 0 0 20
2WRQ_Y 0.00 0.00 0.00 0 2850 0 0 0 0 17
2XKV_B 0.00 0.00 0.00 0 4560 0 0 0 0 20
2XQD_Y 0.00 0.00 0.00 0 2850 0 0 0 0 27
2XXA_G 0.00 0.00 0.00 0 5151 0 0 0 0 42
3A2K_C 0.00 0.00 0.00 0 2926 0 0 0 0 28
3AMU_B 0.00 0.00 0.00 0 3003 0 0 0 0 27
3G4S_9 0.00 0.00 0.00 0 7381 0 0 0 0 57
3GX2_A 0.00 0.00 0.00 0 4371 0 0 0 0 40
3IVN_B 0.00 0.00 0.00 0 2346 0 0 0 0 31
3IZ4_A 0.00 0.00 0.00 0 70876 0 0 0 0 132
3IZF_C 0.00 0.00 0.00 0 6903 0 0 0 0 54
3J20_0 0.00 0.00 0.00 0 2850 0 0 0 0 30
3J20_1 0.00 0.00 0.00 0 2926 0 0 0 0 23
3J2L_3 0.00 0.00 0.00 0 7875 0 0 0 0 53
3JYV_7 0.00 0.00 0.00 0 2850 0 0 0 0 32
3JYX_4 0.00 0.00 0.00 0 12246 0 0 0 0 33
3JYX_3 0.00 0.00 0.00 0 6328 0 0 0 0 27
3LA5_A 0.00 0.00 0.00 0 2485 0 0 0 0 34
3NPB_A 0.00 0.00 0.00 0 7021 0 0 0 0 46
3O58_2 0.00 0.00 0.00 0 7260 0 0 0 0 38
3O58_3 0.00 0.00 0.00 0 12403 0 0 0 0 35
3PDR_A 0.00 0.00 0.00 0 12880 0 0 0 0 72
3RKF_A 0.00 0.00 0.00 0 2211 0 0 0 0 34
3SD1_A 0.00 0.00 0.00 0 3916 0 0 0 0 42
3ZEX_C 0.00 0.00 0.00 0 14196 0 0 0 0 52
3ZEX_D 0.00 0.00 0.00 0 7021 0 0 0 0 49
4A1C_3 0.00 0.00 0.00 0 7140 0 0 0 0 54
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19
4FRG_B 0.00 0.00 0.00 0 3486 0 0 0 0 32

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.