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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MaxExpect - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for MaxExpect & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric MaxExpect CMfinder(20)
MCC 0.553 > 0.546
Average MCC ± 95% Confidence Intervals 0.513 ± 0.286 < 0.560 ± 0.222
Sensitivity 0.470 > 0.366
Positive Predictive Value 0.658 < 0.822
Total TP 77 > 60
Total TN 21115 < 21159
Total FP 43 > 15
Total FP CONTRA 2 > 1
Total FP INCONS 38 > 12
Total FP COMP 3 > 2
Total FN 87 < 104
P-value 0.0

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Performance plots


  1. Comparison of performance of MaxExpect and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MaxExpect and CMfinder(20)).

  2. Comparison of performance of MaxExpect and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MaxExpect and CMfinder(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for MaxExpect and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MaxExpect and CMfinder(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for MaxExpect and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MaxExpect and CMfinder(20)).

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Performance of MaxExpect - scored higher in this pairwise comparison

1. Total counts & total scores for MaxExpect

Total Base Pair Counts
Total TP 77
Total TN 21115
Total FP 43
Total FP CONTRA 2
Total FP INCONS 38
Total FP COMP 3
Total FN 87
Total Scores
MCC 0.553
Average MCC ± 95% Confidence Intervals 0.513 ± 0.286
Sensitivity 0.470
Positive Predictive Value 0.658
Nr of predictions 4

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2. Individual counts for MaxExpect [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.44 0.40 0.50 12 2826 13 0 12 1 18
3J2L_3 0.62 0.53 0.74 28 7837 12 0 10 2 25
3ZEX_D 0.69 0.61 0.79 30 6983 8 1 7 0 19
4FRG_B 0.30 0.22 0.41 7 3469 10 1 9 0 25

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 60
Total TN 21159
Total FP 15
Total FP CONTRA 1
Total FP INCONS 12
Total FP COMP 2
Total FN 104
Total Scores
MCC 0.546
Average MCC ± 95% Confidence Intervals 0.560 ± 0.222
Sensitivity 0.366
Positive Predictive Value 0.822
Nr of predictions 4

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.75 0.57 1.00 17 2833 1 0 0 1 13
3J2L_3 0.45 0.32 0.63 17 7848 11 1 9 1 36
3ZEX_D 0.58 0.39 0.86 19 6999 3 0 3 0 30
4FRG_B 0.47 0.22 1.00 7 3479 0 0 0 0 25

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.