CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MaxExpect - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for MaxExpect & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric MaxExpect Carnac(seed)
MCC 0.579 > 0.402
Average MCC ± 95% Confidence Intervals 0.636 ± 0.094 > 0.135 ± 0.097
Sensitivity 0.507 > 0.180
Positive Predictive Value 0.661 < 0.900
Total TP 863 > 306
Total TN 1271414 < 1272380
Total FP 527 > 36
Total FP CONTRA 37 > 3
Total FP INCONS 406 > 31
Total FP COMP 84 > 2
Total FN 838 < 1395
P-value 3.56938820447e-08

^top




Performance plots


  1. Comparison of performance of MaxExpect and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MaxExpect and Carnac(seed)).

  2. Comparison of performance of MaxExpect and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MaxExpect and Carnac(seed)).

  3. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for MaxExpect and Carnac(seed)).

  4. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for MaxExpect and Carnac(seed)).

  5. Comparison of average Matthews Correlation Coefficients (MCCs) for MaxExpect and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MaxExpect and Carnac(seed)).

  6. Comparison of average Matthews Correlation Coefficients (MCCs) for MaxExpect and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MaxExpect and Carnac(seed)).

^top





Performance of MaxExpect - scored higher in this pairwise comparison

1. Total counts & total scores for MaxExpect

Total Base Pair Counts
Total TP 863
Total TN 1271414
Total FP 527
Total FP CONTRA 37
Total FP INCONS 406
Total FP COMP 84
Total FN 838
Total Scores
MCC 0.579
Average MCC ± 95% Confidence Intervals 0.636 ± 0.094
Sensitivity 0.507
Positive Predictive Value 0.661
Nr of predictions 33

^top



2. Individual counts for MaxExpect [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KE6_A 0.92 0.89 0.94 17 1110 2 0 1 1 2
2KUR_A 0.90 0.86 0.95 18 1109 1 0 1 0 3
2KUU_A 0.87 0.81 0.94 17 1110 2 0 1 1 4
2KUV_A 0.88 0.82 0.95 18 1109 1 0 1 0 4
2KUW_A 0.90 0.86 0.95 18 1109 1 0 1 0 3
2L1F_A 0.98 0.96 1.00 23 2057 0 0 0 0 1
2L1F_B 0.98 0.96 1.00 24 2121 0 0 0 0 1
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
2XKV_B 0.51 0.50 0.53 10 4541 24 0 9 15 10
2XXA_G 0.25 0.24 0.27 10 5114 27 1 26 0 32
3GX2_A 0.77 0.63 0.96 25 4345 2 0 1 1 15
3IVN_B 0.78 0.61 1.00 19 2327 0 0 0 0 12
3IZF_C 0.71 0.61 0.83 33 6863 7 1 6 0 21
3J20_2 0.49 0.44 0.56 276 1116272 221 10 207 4 357
3JYX_4 0.31 0.30 0.31 10 12214 34 4 18 12 23
3JYX_3 0.64 0.63 0.65 17 6302 19 1 8 10 10
3LA5_A 0.78 0.62 1.00 21 2464 0 0 0 0 13
3NPB_A 0.71 0.61 0.82 28 6987 9 0 6 3 18
3O58_3 0.35 0.34 0.35 12 12369 35 2 20 13 23
3O58_2 0.75 0.76 0.74 29 7221 11 3 7 1 9
3PDR_A 0.76 0.63 0.94 45 12832 5 0 3 2 27
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.58 0.48 0.71 20 3888 8 1 7 0 22
3W3S_B 0.88 0.78 1.00 31 4722 1 0 0 1 9
3ZEX_C 0.41 0.27 0.64 14 14174 16 2 6 8 38
4A1C_3 0.69 0.57 0.84 31 7103 6 0 6 0 23
4A1C_2 0.14 0.15 0.14 5 11746 41 4 26 11 28
4AOB_A 0.50 0.40 0.63 17 4344 11 2 8 1 25
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.31 0.26 0.38 5 1313 8 1 7 0 14
4FRG_B 0.30 0.22 0.41 7 3469 10 1 9 0 25
4FRN_A 0.45 0.36 0.57 13 5128 10 2 8 0 23

^top



Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 306
Total TN 1272380
Total FP 36
Total FP CONTRA 3
Total FP INCONS 31
Total FP COMP 2
Total FN 1395
Total Scores
MCC 0.402
Average MCC ± 95% Confidence Intervals 0.135 ± 0.097
Sensitivity 0.180
Positive Predictive Value 0.900
Nr of predictions 33

^top



2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KE6_A 0.00 0.00 0.00 0 1128 0 0 0 0 19
2KUR_A 0.57 0.33 1.00 7 1121 0 0 0 0 14
2KUU_A 0.57 0.33 1.00 7 1121 0 0 0 0 14
2KUV_A 0.64 0.41 1.00 9 1119 0 0 0 0 13
2KUW_A 0.65 0.43 1.00 9 1119 0 0 0 0 12
2L1F_A 0.00 0.00 0.00 0 2080 0 0 0 0 24
2L1F_B 0.00 0.00 0.00 0 2145 0 0 0 0 25
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2LC8_A 0.44 0.20 1.00 4 1536 0 0 0 0 16
2XKV_B 0.00 0.00 0.00 0 4560 0 0 0 0 20
2XXA_G 0.00 0.00 0.00 0 5151 0 0 0 0 42
3GX2_A 0.00 0.00 0.00 0 4371 0 0 0 0 40
3IVN_B 0.00 0.00 0.00 0 2346 0 0 0 0 31
3IZF_C 0.00 0.00 0.00 0 6903 0 0 0 0 54
3J20_2 0.59 0.40 0.88 251 1116480 36 3 31 2 382
3JYX_4 0.00 0.00 0.00 0 12246 0 0 0 0 33
3JYX_3 0.00 0.00 0.00 0 6328 0 0 0 0 27
3LA5_A 0.00 0.00 0.00 0 2485 0 0 0 0 34
3NPB_A 0.00 0.00 0.00 0 7021 0 0 0 0 46
3O58_3 0.00 0.00 0.00 0 12403 0 0 0 0 35
3O58_2 0.00 0.00 0.00 0 7260 0 0 0 0 38
3PDR_A 0.00 0.00 0.00 0 12880 0 0 0 0 72
3RKF_A 0.00 0.00 0.00 0 2211 0 0 0 0 34
3SD1_A 0.00 0.00 0.00 0 3916 0 0 0 0 42
3W3S_B 0.00 0.00 0.00 0 4753 0 0 0 0 40
3ZEX_C 0.00 0.00 0.00 0 14196 0 0 0 0 52
4A1C_3 0.00 0.00 0.00 0 7140 0 0 0 0 54
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19
4FRG_B 0.00 0.00 0.00 0 3486 0 0 0 0 32
4FRN_A 0.00 0.00 0.00 0 5151 0 0 0 0 36

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.