CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of Afold - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & Afold [.zip] - may take several seconds...


Overview

Metric Multilign(seed) Afold
MCC 0.693 > 0.680
Average MCC ± 95% Confidence Intervals 0.628 ± 0.684 < 0.712 ± 0.327
Sensitivity 0.579 < 0.596
Positive Predictive Value 0.835 > 0.782
Total TP 66 < 68
Total TN 9415 > 9407
Total FP 14 < 21
Total FP CONTRA 1 = 1
Total FP INCONS 12 < 18
Total FP COMP 1 < 2
Total FN 48 > 46
P-value 0.0

^top




Performance plots


  1. Comparison of performance of Multilign(seed) and Afold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and Afold).

  2. Comparison of performance of Multilign(seed) and Afold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and Afold).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and Afold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and Afold).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and Afold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and Afold).

^top





Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 66
Total TN 9415
Total FP 14
Total FP CONTRA 1
Total FP INCONS 12
Total FP COMP 1
Total FN 48
Total Scores
MCC 0.693
Average MCC ± 95% Confidence Intervals 0.628 ± 0.684
Sensitivity 0.579
Positive Predictive Value 0.835
Nr of predictions 4

^top



2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.85 1.00 17 973 0 0 0 0 3
2LC8_A -0.01 0.00 0.00 0 1528 12 1 11 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3W3S_B 0.84 0.73 0.97 29 4723 2 0 1 1 11

^top



Performance of Afold - scored lower in this pairwise comparison

1. Total counts & total scores for Afold

Total Base Pair Counts
Total TP 68
Total TN 9407
Total FP 21
Total FP CONTRA 1
Total FP INCONS 18
Total FP COMP 2
Total FN 46
Total Scores
MCC 0.680
Average MCC ± 95% Confidence Intervals 0.712 ± 0.327
Sensitivity 0.596
Positive Predictive Value 0.782
Nr of predictions 4

^top



2. Individual counts for Afold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2LC8_A 0.61 0.55 0.69 11 1524 6 0 5 1 9
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3W3S_B 0.50 0.45 0.56 18 4721 15 1 13 1 22

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.