CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & CRWrnafold [.zip] - may take several seconds...


Overview

Metric Multilign(seed) CRWrnafold
MCC 0.465 > 0.443
Average MCC ± 95% Confidence Intervals 0.383 ± 0.849 > 0.367 ± 0.819
Sensitivity 0.365 < 0.375
Positive Predictive Value 0.603 > 0.534
Total TP 38 < 39
Total TN 9764 > 9754
Total FP 26 < 35
Total FP CONTRA 2 < 6
Total FP INCONS 23 < 28
Total FP COMP 1 = 1
Total FN 66 > 65
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and CRWrnafold).

  2. Comparison of performance of Multilign(seed) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and CRWrnafold).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and CRWrnafold).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and CRWrnafold).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 38
Total TN 9764
Total FP 26
Total FP CONTRA 2
Total FP INCONS 23
Total FP COMP 1
Total FN 66
Total Scores
MCC 0.465
Average MCC ± 95% Confidence Intervals 0.383 ± 0.849
Sensitivity 0.365
Positive Predictive Value 0.603
Nr of predictions 3

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1528 12 1 11 0 20
3SD1_A 0.55 0.45 0.68 19 3888 9 1 8 0 23
4AOB_A 0.61 0.45 0.83 19 4348 5 0 4 1 23

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 39
Total TN 9754
Total FP 35
Total FP CONTRA 6
Total FP INCONS 28
Total FP COMP 1
Total FN 65
Total Scores
MCC 0.443
Average MCC ± 95% Confidence Intervals 0.367 ± 0.819
Sensitivity 0.375
Positive Predictive Value 0.534
Nr of predictions 3

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
3SD1_A 0.52 0.45 0.61 19 3885 12 2 10 0 23
4AOB_A 0.59 0.48 0.74 20 4344 8 2 5 1 22

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.