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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of Murlet(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & Murlet(20) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) Murlet(20)
MCC 0.608 > 0.586
Average MCC ± 95% Confidence Intervals 0.648 ± 0.251 > 0.593 ± 0.198
Sensitivity 0.468 > 0.447
Positive Predictive Value 0.795 > 0.773
Total TP 89 > 85
Total TN 25572 < 25574
Total FP 24 < 29
Total FP CONTRA 4 > 2
Total FP INCONS 19 < 23
Total FP COMP 1 < 4
Total FN 101 < 105
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and Murlet(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and Murlet(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and Murlet(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and Murlet(20)).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 89
Total TN 25572
Total FP 24
Total FP CONTRA 4
Total FP INCONS 19
Total FP COMP 1
Total FN 101
Total Scores
MCC 0.608
Average MCC ± 95% Confidence Intervals 0.648 ± 0.251
Sensitivity 0.468
Positive Predictive Value 0.795
Nr of predictions 5

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.85 1.00 17 973 0 0 0 0 3
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.55 0.45 0.68 19 3888 9 1 8 0 23
3ZEX_C 0.39 0.27 0.58 14 14172 10 3 7 0 38
4AOB_A 0.61 0.45 0.83 19 4348 5 0 4 1 23

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Performance of Murlet(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 85
Total TN 25574
Total FP 29
Total FP CONTRA 2
Total FP INCONS 23
Total FP COMP 4
Total FN 105
Total Scores
MCC 0.586
Average MCC ± 95% Confidence Intervals 0.593 ± 0.198
Sensitivity 0.447
Positive Predictive Value 0.773
Nr of predictions 5

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2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.53 0.50 0.59 10 973 7 0 7 0 10
3RKF_A 0.68 0.47 1.00 16 2195 0 0 0 0 18
3SD1_A 0.68 0.57 0.83 24 3887 5 1 4 0 18
3ZEX_C 0.34 0.23 0.50 12 14172 15 1 11 3 40
4AOB_A 0.72 0.55 0.96 23 4347 2 0 1 1 19

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.