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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of PETfold_2.0(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & PETfold_2.0(seed) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) PETfold_2.0(seed)
MCC 0.873 > 0.782
Average MCC ± 95% Confidence Intervals 0.873 ± > 0.782 ±
Sensitivity 0.789 > 0.684
Positive Predictive Value 0.968 > 0.897
Total TP 30 > 26
Total TN 4155 < 4157
Total FP 1 < 4
Total FP CONTRA 1 = 1
Total FP INCONS 0 < 2
Total FP COMP 0 < 1
Total FN 8 < 12
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and PETfold_2.0(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and PETfold_2.0(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and PETfold_2.0(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and PETfold_2.0(seed)).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 30
Total TN 4155
Total FP 1
Total FP CONTRA 1
Total FP INCONS 0
Total FP COMP 0
Total FN 8
Total Scores
MCC 0.873
Average MCC ± 95% Confidence Intervals 0.873 ±
Sensitivity 0.789
Positive Predictive Value 0.968
Nr of predictions 1

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3W1K_J 0.87 0.79 0.97 30 4155 1 1 0 0 8

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Performance of PETfold_2.0(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for PETfold_2.0(seed)

Total Base Pair Counts
Total TP 26
Total TN 4157
Total FP 4
Total FP CONTRA 1
Total FP INCONS 2
Total FP COMP 1
Total FN 12
Total Scores
MCC 0.782
Average MCC ± 95% Confidence Intervals 0.782 ±
Sensitivity 0.684
Positive Predictive Value 0.897
Nr of predictions 1

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2. Individual counts for PETfold_2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3W1K_J 0.78 0.68 0.90 26 4157 4 1 2 1 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.