CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of RNASampler(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & RNASampler(20) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) RNASampler(20)
MCC 0.608 > 0.597
Average MCC ± 95% Confidence Intervals 0.648 ± 0.251 > 0.642 ± 0.301
Sensitivity 0.468 > 0.447
Positive Predictive Value 0.795 < 0.802
Total TP 89 > 85
Total TN 25572 < 25578
Total FP 24 < 26
Total FP CONTRA 4 > 1
Total FP INCONS 19 < 20
Total FP COMP 1 < 5
Total FN 101 < 105
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and RNASampler(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and RNASampler(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and RNASampler(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and RNASampler(20)).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 89
Total TN 25572
Total FP 24
Total FP CONTRA 4
Total FP INCONS 19
Total FP COMP 1
Total FN 101
Total Scores
MCC 0.608
Average MCC ± 95% Confidence Intervals 0.648 ± 0.251
Sensitivity 0.468
Positive Predictive Value 0.795
Nr of predictions 5

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.85 1.00 17 973 0 0 0 0 3
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.55 0.45 0.68 19 3888 9 1 8 0 23
3ZEX_C 0.39 0.27 0.58 14 14172 10 3 7 0 38
4AOB_A 0.61 0.45 0.83 19 4348 5 0 4 1 23

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Performance of RNASampler(20) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(20)

Total Base Pair Counts
Total TP 85
Total TN 25578
Total FP 26
Total FP CONTRA 1
Total FP INCONS 20
Total FP COMP 5
Total FN 105
Total Scores
MCC 0.597
Average MCC ± 95% Confidence Intervals 0.642 ± 0.301
Sensitivity 0.447
Positive Predictive Value 0.802
Nr of predictions 5

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2. Individual counts for RNASampler(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.90 0.95 18 971 1 0 1 0 2
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.67 0.48 0.95 20 3895 1 0 1 0 22
3ZEX_C 0.27 0.19 0.38 10 14170 20 1 15 4 42
4AOB_A 0.58 0.40 0.85 17 4351 4 0 3 1 25

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.