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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of RSpredict(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & RSpredict(20) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) RSpredict(20)
MCC 0.542 > 0.423
Average MCC ± 95% Confidence Intervals 0.561 ± 0.292 > 0.421 ± 0.307
Sensitivity 0.413 > 0.323
Positive Predictive Value 0.719 > 0.563
Total TP 92 > 72
Total TN 33059 = 33059
Total FP 37 < 56
Total FP CONTRA 9 > 7
Total FP INCONS 27 < 49
Total FP COMP 1 > 0
Total FN 131 < 151
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and RSpredict(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and RSpredict(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and RSpredict(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and RSpredict(20)).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 92
Total TN 33059
Total FP 37
Total FP CONTRA 9
Total FP INCONS 27
Total FP COMP 1
Total FN 131
Total Scores
MCC 0.542
Average MCC ± 95% Confidence Intervals 0.561 ± 0.292
Sensitivity 0.413
Positive Predictive Value 0.719
Nr of predictions 6

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.85 1.00 17 973 0 0 0 0 3
3J3E_8 0.13 0.09 0.19 3 7487 13 5 8 0 30
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.55 0.45 0.68 19 3888 9 1 8 0 23
3ZEX_C 0.39 0.27 0.58 14 14172 10 3 7 0 38
4AOB_A 0.61 0.45 0.83 19 4348 5 0 4 1 23

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Performance of RSpredict(20) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(20)

Total Base Pair Counts
Total TP 72
Total TN 33059
Total FP 56
Total FP CONTRA 7
Total FP INCONS 49
Total FP COMP 0
Total FN 151
Total Scores
MCC 0.423
Average MCC ± 95% Confidence Intervals 0.421 ± 0.307
Sensitivity 0.323
Positive Predictive Value 0.563
Nr of predictions 6

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2. Individual counts for RSpredict(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.55 0.50 0.63 10 974 6 0 6 0 10
3J3E_8 0.00 0.00 0.00 0 7484 19 4 15 0 33
3RKF_A 0.77 0.62 0.95 21 2189 1 0 1 0 13
3SD1_A 0.68 0.60 0.78 25 3884 7 1 6 0 17
3ZEX_C 0.26 0.19 0.36 10 14168 18 2 16 0 42
4AOB_A 0.28 0.14 0.55 6 4360 5 0 5 0 36

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.