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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of Vsfold4 - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & Vsfold4 [.zip] - may take several seconds...


Overview

Metric Multilign(seed) Vsfold4
MCC 0.645 > 0.493
Average MCC ± 95% Confidence Intervals 0.612 ± 0.351 > 0.493 ± 0.375
Sensitivity 0.525 > 0.409
Positive Predictive Value 0.800 > 0.604
Total TP 104 > 81
Total TN 17651 > 17647
Total FP 28 < 55
Total FP CONTRA 2 = 2
Total FP INCONS 24 < 51
Total FP COMP 2 = 2
Total FN 94 < 117
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and Vsfold4. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and Vsfold4).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and Vsfold4. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and Vsfold4).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 104
Total TN 17651
Total FP 28
Total FP CONTRA 2
Total FP INCONS 24
Total FP COMP 2
Total FN 94
Total Scores
MCC 0.645
Average MCC ± 95% Confidence Intervals 0.612 ± 0.351
Sensitivity 0.525
Positive Predictive Value 0.800
Nr of predictions 6

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.85 1.00 17 973 0 0 0 0 3
2LC8_A -0.01 0.00 0.00 0 1528 12 1 11 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.55 0.45 0.68 19 3888 9 1 8 0 23
3W3S_B 0.84 0.73 0.97 29 4723 2 0 1 1 11
4AOB_A 0.61 0.45 0.83 19 4348 5 0 4 1 23

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Performance of Vsfold4 - scored lower in this pairwise comparison

1. Total counts & total scores for Vsfold4

Total Base Pair Counts
Total TP 81
Total TN 17647
Total FP 55
Total FP CONTRA 2
Total FP INCONS 51
Total FP COMP 2
Total FN 117
Total Scores
MCC 0.493
Average MCC ± 95% Confidence Intervals 0.493 ± 0.375
Sensitivity 0.409
Positive Predictive Value 0.604
Nr of predictions 6

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2. Individual counts for Vsfold4 [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.85 1.00 17 973 0 0 0 0 3
2LC8_A -0.01 0.00 0.00 0 1527 13 0 13 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.19 0.17 0.24 7 3887 22 1 21 0 35
3W3S_B 0.67 0.58 0.79 23 4724 7 0 6 1 17
4AOB_A 0.42 0.33 0.54 14 4345 13 1 11 1 28

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.