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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(20) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(20) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric Murlet(20) CMfinder(20)
MCC 0.600 > 0.546
Average MCC ± 95% Confidence Intervals 0.553 ± 0.423 < 0.560 ± 0.222
Sensitivity 0.463 > 0.366
Positive Predictive Value 0.784 < 0.822
Total TP 76 > 60
Total TN 21135 < 21159
Total FP 23 > 15
Total FP CONTRA 1 = 1
Total FP INCONS 20 > 12
Total FP COMP 2 = 2
Total FN 88 < 104
P-value 0.0

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Performance plots


  1. Comparison of performance of Murlet(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(20) and CMfinder(20)).

  2. Comparison of performance of Murlet(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(20) and CMfinder(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(20) and CMfinder(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(20) and CMfinder(20)).

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Performance of Murlet(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 76
Total TN 21135
Total FP 23
Total FP CONTRA 1
Total FP INCONS 20
Total FP COMP 2
Total FN 88
Total Scores
MCC 0.600
Average MCC ± 95% Confidence Intervals 0.553 ± 0.423
Sensitivity 0.463
Positive Predictive Value 0.784
Nr of predictions 4

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2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.58 0.47 0.74 14 2831 5 0 5 0 16
3J2L_3 0.69 0.49 0.96 26 7848 3 0 1 2 27
3ZEX_D 0.77 0.65 0.91 32 6986 3 0 3 0 17
4FRG_B 0.17 0.13 0.25 4 3470 12 1 11 0 28

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 60
Total TN 21159
Total FP 15
Total FP CONTRA 1
Total FP INCONS 12
Total FP COMP 2
Total FN 104
Total Scores
MCC 0.546
Average MCC ± 95% Confidence Intervals 0.560 ± 0.222
Sensitivity 0.366
Positive Predictive Value 0.822
Nr of predictions 4

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.75 0.57 1.00 17 2833 1 0 0 1 13
3J2L_3 0.45 0.32 0.63 17 7848 11 1 9 1 36
3ZEX_D 0.58 0.39 0.86 19 6999 3 0 3 0 30
4FRG_B 0.47 0.22 1.00 7 3479 0 0 0 0 25

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.