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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(seed) - scored higher in this pairwise comparison

  4. Performance of Mastr(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(seed) & Mastr(20) [.zip] - may take several seconds...


Overview

Metric Murlet(seed) Mastr(20)
MCC 0.463 > 0.430
Average MCC ± 95% Confidence Intervals 0.469 ± 0.058 > 0.395 ± 0.157
Sensitivity 0.250 > 0.237
Positive Predictive Value 0.863 > 0.784
Total TP 164 > 156
Total TN 107231 > 107222
Total FP 32 < 49
Total FP CONTRA 5 > 3
Total FP INCONS 21 < 40
Total FP COMP 6 = 6
Total FN 493 < 501
P-value 3.66763272401e-08

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Performance plots


  1. Comparison of performance of Murlet(seed) and Mastr(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(seed) and Mastr(20)).

  2. Comparison of performance of Murlet(seed) and Mastr(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(seed) and Mastr(20)).

  3. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Murlet(seed) and Mastr(20)).

  4. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Murlet(seed) and Mastr(20)).

  5. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(seed) and Mastr(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(seed) and Mastr(20)).

  6. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(seed) and Mastr(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(seed) and Mastr(20)).

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Performance of Murlet(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 164
Total TN 107231
Total FP 32
Total FP CONTRA 5
Total FP INCONS 21
Total FP COMP 6
Total FN 493
Total Scores
MCC 0.463
Average MCC ± 95% Confidence Intervals 0.469 ± 0.058
Sensitivity 0.250
Positive Predictive Value 0.863
Nr of predictions 19

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.52 0.27 1.00 3 403 0 0 0 0 8
2L94_A 0.59 0.40 0.89 8 981 1 0 1 0 12
2XKV_B 0.45 0.20 1.00 4 4556 2 0 0 2 16
2XXA_G 0.38 0.14 1.00 6 5145 0 0 0 0 36
3GX2_A 0.59 0.35 1.00 14 4357 1 0 0 1 26
3IVN_B 0.53 0.39 0.75 12 2330 4 2 2 0 19
3JYX_4 0.23 0.09 0.60 3 12241 4 0 2 2 30
3LA5_A 0.58 0.41 0.82 14 2468 3 1 2 0 20
3NPB_A 0.49 0.28 0.87 13 7006 2 1 1 0 33
3O58_3 0.45 0.20 1.00 7 12396 0 0 0 0 28
3PDR_A 0.44 0.19 1.00 14 12866 0 0 0 0 58
3RKF_A 0.53 0.35 0.80 12 2196 3 1 2 0 22
3SD1_A 0.47 0.26 0.85 11 3903 2 0 2 0 31
3ZEX_C 0.37 0.13 1.00 7 14189 0 0 0 0 45
4A1C_2 0.46 0.21 1.00 7 11774 0 0 0 0 26
4AOB_A 0.58 0.33 1.00 14 4357 1 0 0 1 28
4ENB_A 0.56 0.32 1.00 6 1269 0 0 0 0 13
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13
4FRG_B 0.15 0.09 0.25 3 3474 9 0 9 0 29

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Performance of Mastr(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 156
Total TN 107222
Total FP 49
Total FP CONTRA 3
Total FP INCONS 40
Total FP COMP 6
Total FN 501
Total Scores
MCC 0.430
Average MCC ± 95% Confidence Intervals 0.395 ± 0.157
Sensitivity 0.237
Positive Predictive Value 0.784
Nr of predictions 19

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2L94_A 0.87 0.80 0.94 16 973 1 0 1 0 4
2XKV_B 0.45 0.20 1.00 4 4556 3 0 0 3 16
2XXA_G 0.41 0.17 1.00 7 5144 0 0 0 0 35
3GX2_A 0.39 0.28 0.55 11 4351 10 0 9 1 29
3IVN_B 0.78 0.65 0.95 20 2325 1 1 0 0 11
3JYX_4 0.00 0.00 0.00 0 12246 0 0 0 0 33
3LA5_A 0.76 0.59 1.00 20 2465 0 0 0 0 14
3NPB_A 0.30 0.24 0.39 11 6993 18 1 16 1 35
3O58_3 0.00 0.00 0.00 0 12403 0 0 0 0 35
3PDR_A 0.00 0.00 0.00 0 12880 0 0 0 0 72
3RKF_A 0.70 0.50 1.00 17 2194 0 0 0 0 17
3SD1_A 0.61 0.50 0.75 21 3888 7 1 6 0 21
3ZEX_C 0.00 0.00 0.00 0 14196 0 0 0 0 52
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.39 0.26 0.58 11 4352 9 0 8 1 31
4ENB_A 0.39 0.16 1.00 3 1272 0 0 0 0 16
4ENC_A 0.51 0.26 1.00 5 1321 0 0 0 0 14
4FRG_B 0.00 0.00 0.00 0 3486 0 0 0 0 32

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.