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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(seed) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(seed) & NanoFolder [.zip] - may take several seconds...


Overview

Metric Murlet(seed) NanoFolder
MCC 0.404 > 0.252
Average MCC ± 95% Confidence Intervals 0.399 ± 0.296 > 0.316 ± 0.298
Sensitivity 0.234 < 0.266
Positive Predictive Value 0.706 > 0.248
Total TP 36 < 41
Total TN 23720 > 23606
Total FP 16 < 135
Total FP CONTRA 0 < 14
Total FP INCONS 15 < 110
Total FP COMP 1 < 11
Total FN 118 > 113
P-value 0.0

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Performance plots


  1. Comparison of performance of Murlet(seed) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(seed) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(seed) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(seed) and NanoFolder).

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Performance of Murlet(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 36
Total TN 23720
Total FP 16
Total FP CONTRA 0
Total FP INCONS 15
Total FP COMP 1
Total FN 118
Total Scores
MCC 0.404
Average MCC ± 95% Confidence Intervals 0.399 ± 0.296
Sensitivity 0.234
Positive Predictive Value 0.706
Nr of predictions 5

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1528 12 0 12 0 20
3W3S_B 0.41 0.23 0.75 9 4741 3 0 3 0 31
4A1C_2 0.46 0.21 1.00 7 11774 0 0 0 0 26
4AOB_A 0.58 0.33 1.00 14 4357 1 0 0 1 28
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 41
Total TN 23606
Total FP 135
Total FP CONTRA 14
Total FP INCONS 110
Total FP COMP 11
Total FN 113
Total Scores
MCC 0.252
Average MCC ± 95% Confidence Intervals 0.316 ± 0.298
Sensitivity 0.266
Positive Predictive Value 0.248
Nr of predictions 5

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.52 0.55 0.50 11 1518 11 0 11 0 9
3W3S_B 0.17 0.18 0.18 7 4713 34 1 32 1 33
4A1C_2 0.00 0.00 0.00 0 11728 61 12 41 8 33
4AOB_A 0.33 0.29 0.39 12 4340 20 1 18 1 30
4ENC_A 0.57 0.58 0.58 11 1307 9 0 8 1 8

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.