CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of NanoFolder - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for NanoFolder & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric NanoFolder Carnac(seed)
MCC 0.308 > 0.138
Average MCC ± 95% Confidence Intervals 0.344 ± 0.236 > 0.074 ± 0.191
Sensitivity 0.317 > 0.019
Positive Predictive Value 0.308 < 1.000
Total TP 66 > 4
Total TN 30697 < 30907
Total FP 159 > 0
Total FP CONTRA 16 > 0
Total FP INCONS 132 > 0
Total FP COMP 11 > 0
Total FN 142 < 204
P-value 0.0

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Performance plots


  1. Comparison of performance of NanoFolder and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for NanoFolder and Carnac(seed)).

  2. Comparison of performance of NanoFolder and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for NanoFolder and Carnac(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for NanoFolder and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for NanoFolder and Carnac(seed)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for NanoFolder and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for NanoFolder and Carnac(seed)).

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Performance of NanoFolder - scored higher in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 66
Total TN 30697
Total FP 159
Total FP CONTRA 16
Total FP INCONS 132
Total FP COMP 11
Total FN 142
Total Scores
MCC 0.308
Average MCC ± 95% Confidence Intervals 0.344 ± 0.236
Sensitivity 0.317
Positive Predictive Value 0.308
Nr of predictions 6

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.52 0.55 0.50 11 1518 11 0 11 0 9
3W3S_B 0.17 0.18 0.18 7 4713 34 1 32 1 33
4A1C_2 0.00 0.00 0.00 0 11728 61 12 41 8 33
4A1C_3 0.48 0.46 0.51 25 7091 24 2 22 0 29
4AOB_A 0.33 0.29 0.39 12 4340 20 1 18 1 30
4ENC_A 0.57 0.58 0.58 11 1307 9 0 8 1 8

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 4
Total TN 30907
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 204
Total Scores
MCC 0.138
Average MCC ± 95% Confidence Intervals 0.074 ± 0.191
Sensitivity 0.019
Positive Predictive Value 1.000
Nr of predictions 6

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.44 0.20 1.00 4 1536 0 0 0 0 16
3W3S_B 0.00 0.00 0.00 0 4753 0 0 0 0 40
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4A1C_3 0.00 0.00 0.00 0 7140 0 0 0 0 54
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.