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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_2.0(seed) - scored higher in this pairwise comparison

  4. Performance of Carnac(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_2.0(seed) & Carnac(20) [.zip] - may take several seconds...


Overview

Metric PETfold_2.0(seed) Carnac(20)
MCC 0.761 > 0.576
Average MCC ± 95% Confidence Intervals 0.761 ± > 0.576 ±
Sensitivity 0.614 > 0.351
Positive Predictive Value 0.946 < 0.952
Total TP 35 > 20
Total TN 6984 < 7000
Total FP 3 > 1
Total FP CONTRA 0 = 0
Total FP INCONS 2 > 1
Total FP COMP 1 > 0
Total FN 22 < 37
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_2.0(seed) and Carnac(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_2.0(seed) and Carnac(20)).

  2. Comparison of performance of PETfold_2.0(seed) and Carnac(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_2.0(seed) and Carnac(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_2.0(seed) and Carnac(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_2.0(seed) and Carnac(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_2.0(seed) and Carnac(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_2.0(seed) and Carnac(20)).

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Performance of PETfold_2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_2.0(seed)

Total Base Pair Counts
Total TP 35
Total TN 6984
Total FP 3
Total FP CONTRA 0
Total FP INCONS 2
Total FP COMP 1
Total FN 22
Total Scores
MCC 0.761
Average MCC ± 95% Confidence Intervals 0.761 ±
Sensitivity 0.614
Positive Predictive Value 0.946
Nr of predictions 1

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2. Individual counts for PETfold_2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3V_B 0.76 0.61 0.95 35 6984 3 0 2 1 22

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Performance of Carnac(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(20)

Total Base Pair Counts
Total TP 20
Total TN 7000
Total FP 1
Total FP CONTRA 0
Total FP INCONS 1
Total FP COMP 0
Total FN 37
Total Scores
MCC 0.576
Average MCC ± 95% Confidence Intervals 0.576 ±
Sensitivity 0.351
Positive Predictive Value 0.952
Nr of predictions 1

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2. Individual counts for Carnac(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3V_B 0.58 0.35 0.95 20 7000 1 0 1 0 37

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.