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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_2.0(seed) - scored higher in this pairwise comparison

  4. Performance of RSpredict(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_2.0(seed) & RSpredict(seed) [.zip] - may take several seconds...


Overview

Metric PETfold_2.0(seed) RSpredict(seed)
MCC 0.782 > 0.513
Average MCC ± 95% Confidence Intervals 0.782 ± > 0.513 ±
Sensitivity 0.684 > 0.289
Positive Predictive Value 0.897 < 0.917
Total TP 26 > 11
Total TN 4157 < 4174
Total FP 4 > 1
Total FP CONTRA 1 > 0
Total FP INCONS 2 > 1
Total FP COMP 1 > 0
Total FN 12 < 27
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_2.0(seed) and RSpredict(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_2.0(seed) and RSpredict(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_2.0(seed) and RSpredict(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_2.0(seed) and RSpredict(seed)).

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Performance of PETfold_2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_2.0(seed)

Total Base Pair Counts
Total TP 26
Total TN 4157
Total FP 4
Total FP CONTRA 1
Total FP INCONS 2
Total FP COMP 1
Total FN 12
Total Scores
MCC 0.782
Average MCC ± 95% Confidence Intervals 0.782 ±
Sensitivity 0.684
Positive Predictive Value 0.897
Nr of predictions 1

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2. Individual counts for PETfold_2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3W1K_J 0.78 0.68 0.90 26 4157 4 1 2 1 12

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Performance of RSpredict(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(seed)

Total Base Pair Counts
Total TP 11
Total TN 4174
Total FP 1
Total FP CONTRA 0
Total FP INCONS 1
Total FP COMP 0
Total FN 27
Total Scores
MCC 0.513
Average MCC ± 95% Confidence Intervals 0.513 ±
Sensitivity 0.289
Positive Predictive Value 0.917
Nr of predictions 1

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2. Individual counts for RSpredict(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3W1K_J 0.51 0.29 0.92 11 4174 1 0 1 0 27

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.