Table of contents:
- Overview
- Performance Plots
- Performance of PETfold_pre2.0(20)
- scored higher in this pairwise comparison
- Performance of PPfold(seed)
- scored lower in this pairwise comparison
- Compile and download dataset for PETfold_pre2.0(20) & PPfold(seed) [.zip] - may take several seconds...
Overview
| Metric |
PETfold_pre2.0(20) |
|
PPfold(seed) |
|---|
| MCC |
0.649 |
>
|
0.077 |
| Average MCC ± 95% Confidence Intervals |
0.629
±
0.122
|
>
|
0.030
±
0.037
|
| Sensitivity |
0.532 |
>
|
0.014 |
| Positive Predictive Value |
0.796 |
>
|
0.429 |
| Total TP |
335 |
>
|
9 |
| Total TN |
103753 |
<
|
104153 |
| Total FP |
114 |
>
|
73 |
| Total FP CONTRA |
3 |
>
|
0 |
| Total FP INCONS |
83 |
>
|
12 |
| Total FP COMP |
28 |
<
|
61 |
| Total FN |
295 |
<
|
621 |
| P-value |
2.89169006118e-08 |
Performance plots
-
Comparison of performance of PETfold_pre2.0(20) and PPfold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data
(individual counts for PETfold_pre2.0(20)
and PPfold(seed)).
-
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data
(individual counts for PETfold_pre2.0(20)
and PPfold(seed)).
-
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and PPfold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data
(individual counts for PETfold_pre2.0(20)
and PPfold(seed)).
Performance of PETfold_pre2.0(20)
- scored higher in this pairwise comparison
1. Total counts & total scores for PETfold_pre2.0(20)
| Total Base Pair Counts |
|---|
| Total TP |
335 |
| Total TN |
103753 |
| Total FP |
114 |
| Total FP CONTRA |
3 |
| Total FP INCONS |
83 |
| Total FP COMP |
28 |
| Total FN |
295 |
| Total Scores |
|---|
| MCC |
0.649 |
| Average MCC ± 95% Confidence Intervals |
0.629
±
0.122
|
| Sensitivity |
0.532 |
| Positive Predictive Value |
0.796 |
| Nr of predictions |
17 |
Performance of PPfold(seed)
- scored lower in this pairwise comparison
1. Total counts & total scores for PPfold(seed)
| Total Base Pair Counts |
|---|
| Total TP |
9 |
| Total TN |
104153 |
| Total FP |
73 |
| Total FP CONTRA |
0 |
| Total FP INCONS |
12 |
| Total FP COMP |
61 |
| Total FN |
621 |
| Total Scores |
|---|
| MCC |
0.077 |
| Average MCC ± 95% Confidence Intervals |
0.030
±
0.037
|
| Sensitivity |
0.014 |
| Positive Predictive Value |
0.429 |
| Nr of predictions |
17 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based
on the paper by Gardener & Giegerich, 2004.
| 
