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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric PPfold(20) CMfinder(20)
MCC 0.788 > 0.546
Average MCC ± 95% Confidence Intervals 0.787 ± 0.074 > 0.560 ± 0.222
Sensitivity 0.652 > 0.366
Positive Predictive Value 0.955 > 0.822
Total TP 107 > 60
Total TN 21120 < 21159
Total FP 7 < 15
Total FP CONTRA 0 < 1
Total FP INCONS 5 < 12
Total FP COMP 2 = 2
Total FN 57 < 104
P-value 0.0

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Performance plots


  1. Comparison of performance of PPfold(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and CMfinder(20)).

  2. Comparison of performance of PPfold(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and CMfinder(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and CMfinder(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and CMfinder(20)).

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Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 107
Total TN 21120
Total FP 7
Total FP CONTRA 0
Total FP INCONS 5
Total FP COMP 2
Total FN 57
Total Scores
MCC 0.788
Average MCC ± 95% Confidence Intervals 0.787 ± 0.074
Sensitivity 0.652
Positive Predictive Value 0.955
Nr of predictions 4

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.70 1.00 21 2829 0 0 0 0 9
3J2L_3 0.78 0.62 0.97 33 7841 3 0 1 2 20
3ZEX_D 0.81 0.71 0.92 35 6983 3 0 3 0 14
4FRG_B 0.73 0.56 0.95 18 3467 1 0 1 0 14

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 60
Total TN 21159
Total FP 15
Total FP CONTRA 1
Total FP INCONS 12
Total FP COMP 2
Total FN 104
Total Scores
MCC 0.546
Average MCC ± 95% Confidence Intervals 0.560 ± 0.222
Sensitivity 0.366
Positive Predictive Value 0.822
Nr of predictions 4

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.75 0.57 1.00 17 2833 1 0 0 1 13
3J2L_3 0.45 0.32 0.63 17 7848 11 1 9 1 36
3ZEX_D 0.58 0.39 0.86 19 6999 3 0 3 0 30
4FRG_B 0.47 0.22 1.00 7 3479 0 0 0 0 25

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.