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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric PPfold(20) Multilign(seed)
MCC 0.613 > 0.608
Average MCC ± 95% Confidence Intervals 0.621 ± 0.208 < 0.648 ± 0.251
Sensitivity 0.453 < 0.468
Positive Predictive Value 0.835 > 0.795
Total TP 86 < 89
Total TN 25581 > 25572
Total FP 20 < 24
Total FP CONTRA 0 < 4
Total FP INCONS 17 < 19
Total FP COMP 3 > 1
Total FN 104 > 101
P-value 0.0

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Performance plots


  1. Comparison of performance of PPfold(20) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and Multilign(seed)).

  2. Comparison of performance of PPfold(20) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and Multilign(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and Multilign(seed)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and Multilign(seed)).

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Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 86
Total TN 25581
Total FP 20
Total FP CONTRA 0
Total FP INCONS 17
Total FP COMP 3
Total FN 104
Total Scores
MCC 0.613
Average MCC ± 95% Confidence Intervals 0.621 ± 0.208
Sensitivity 0.453
Positive Predictive Value 0.835
Nr of predictions 5

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.63 0.45 0.90 9 980 1 0 1 0 11
3RKF_A 0.73 0.56 0.95 19 2191 1 0 1 0 15
3SD1_A 0.68 0.52 0.88 22 3891 3 0 3 0 20
3ZEX_C 0.33 0.21 0.52 11 14175 12 0 10 2 41
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17

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Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 89
Total TN 25572
Total FP 24
Total FP CONTRA 4
Total FP INCONS 19
Total FP COMP 1
Total FN 101
Total Scores
MCC 0.608
Average MCC ± 95% Confidence Intervals 0.648 ± 0.251
Sensitivity 0.468
Positive Predictive Value 0.795
Nr of predictions 5

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.85 1.00 17 973 0 0 0 0 3
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.55 0.45 0.68 19 3888 9 1 8 0 23
3ZEX_C 0.39 0.27 0.58 14 14172 10 3 7 0 38
4AOB_A 0.61 0.45 0.83 19 4348 5 0 4 1 23

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.