CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric RNASLOpt Carnac(seed)
MCC 0.462 > 0.107
Average MCC ± 95% Confidence Intervals 0.489 ± 0.168 > 0.044 ± 0.101
Sensitivity 0.378 > 0.012
Positive Predictive Value 0.572 < 1.000
Total TP 131 > 4
Total TN 54790 < 55015
Total FP 118 > 0
Total FP CONTRA 16 > 0
Total FP INCONS 82 > 0
Total FP COMP 20 > 0
Total FN 216 < 343
P-value 1.75835195567e-08

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Performance plots


  1. Comparison of performance of RNASLOpt and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and Carnac(seed)).

  2. Comparison of performance of RNASLOpt and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and Carnac(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and Carnac(seed)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and Carnac(seed)).

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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 131
Total TN 54790
Total FP 118
Total FP CONTRA 16
Total FP INCONS 82
Total FP COMP 20
Total FN 216
Total Scores
MCC 0.462
Average MCC ± 95% Confidence Intervals 0.489 ± 0.168
Sensitivity 0.378
Positive Predictive Value 0.572
Nr of predictions 10

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.35 0.64 7 1529 4 0 4 0 13
3W3S_B 0.82 0.70 0.97 28 4724 2 0 1 1 12
3ZEX_C 0.26 0.21 0.33 11 14163 35 2 20 13 41
4A1C_2 0.23 0.24 0.22 8 11744 35 8 21 6 25
4A1C_3 0.67 0.52 0.88 28 7108 4 0 4 0 26
4AOB_A 0.26 0.19 0.38 8 4350 13 2 11 0 34
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10
4FRG_B 0.56 0.47 0.68 15 3464 7 1 6 0 17
4FRN_A 0.20 0.17 0.26 6 5128 17 2 15 0 30

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 4
Total TN 55015
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 343
Total Scores
MCC 0.107
Average MCC ± 95% Confidence Intervals 0.044 ± 0.101
Sensitivity 0.012
Positive Predictive Value 1.000
Nr of predictions 10

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.44 0.20 1.00 4 1536 0 0 0 0 16
3W3S_B 0.00 0.00 0.00 0 4753 0 0 0 0 40
3ZEX_C 0.00 0.00 0.00 0 14196 0 0 0 0 52
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4A1C_3 0.00 0.00 0.00 0 7140 0 0 0 0 54
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19
4FRG_B 0.00 0.00 0.00 0 3486 0 0 0 0 32
4FRN_A 0.00 0.00 0.00 0 5151 0 0 0 0 36

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.