CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric RNASLOpt RNASampler(seed)
MCC 0.425 > 0.317
Average MCC ± 95% Confidence Intervals 0.445 ± 0.433 > 0.291 ± 0.363
Sensitivity 0.372 > 0.207
Positive Predictive Value 0.491 < 0.492
Total TP 54 > 30
Total TN 32160 < 32209
Total FP 76 > 44
Total FP CONTRA 10 > 1
Total FP INCONS 46 > 30
Total FP COMP 20 > 13
Total FN 91 < 115
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASLOpt and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and RNASampler(seed)).

  2. Comparison of performance of RNASLOpt and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and RNASampler(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and RNASampler(seed)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and RNASampler(seed)).

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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 54
Total TN 32160
Total FP 76
Total FP CONTRA 10
Total FP INCONS 46
Total FP COMP 20
Total FN 91
Total Scores
MCC 0.425
Average MCC ± 95% Confidence Intervals 0.445 ± 0.433
Sensitivity 0.372
Positive Predictive Value 0.491
Nr of predictions 4

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.35 0.64 7 1529 4 0 4 0 13
3W3S_B 0.82 0.70 0.97 28 4724 2 0 1 1 12
3ZEX_C 0.26 0.21 0.33 11 14163 35 2 20 13 41
4A1C_2 0.23 0.24 0.22 8 11744 35 8 21 6 25

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 30
Total TN 32209
Total FP 44
Total FP CONTRA 1
Total FP INCONS 30
Total FP COMP 13
Total FN 115
Total Scores
MCC 0.317
Average MCC ± 95% Confidence Intervals 0.291 ± 0.363
Sensitivity 0.207
Positive Predictive Value 0.492
Nr of predictions 4

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1530 10 0 10 0 20
3W3S_B 0.55 0.30 1.00 12 4741 1 0 0 1 28
3ZEX_C 0.32 0.19 0.53 10 14177 13 1 8 4 42
4A1C_2 0.31 0.24 0.40 8 11761 20 0 12 8 25

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.