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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(20) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(20) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric RNASampler(20) CMfinder(20)
MCC 0.607 > 0.546
Average MCC ± 95% Confidence Intervals 0.620 ± 0.241 > 0.560 ± 0.222
Sensitivity 0.451 > 0.366
Positive Predictive Value 0.822 > 0.822
Total TP 74 > 60
Total TN 21142 < 21159
Total FP 19 > 15
Total FP CONTRA 1 = 1
Total FP INCONS 15 > 12
Total FP COMP 3 > 2
Total FN 90 < 104
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(20) and CMfinder(20)).

  2. Comparison of performance of RNASampler(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(20) and CMfinder(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(20) and CMfinder(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(20) and CMfinder(20)).

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Performance of RNASampler(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(20)

Total Base Pair Counts
Total TP 74
Total TN 21142
Total FP 19
Total FP CONTRA 1
Total FP INCONS 15
Total FP COMP 3
Total FN 90
Total Scores
MCC 0.607
Average MCC ± 95% Confidence Intervals 0.620 ± 0.241
Sensitivity 0.451
Positive Predictive Value 0.822
Nr of predictions 4

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2. Individual counts for RNASampler(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.80 0.67 0.95 20 2829 2 0 1 1 10
3J2L_3 0.45 0.32 0.63 17 7848 12 1 9 2 36
3ZEX_D 0.68 0.49 0.96 24 6996 1 0 1 0 25
4FRG_B 0.55 0.41 0.76 13 3469 4 0 4 0 19

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 60
Total TN 21159
Total FP 15
Total FP CONTRA 1
Total FP INCONS 12
Total FP COMP 2
Total FN 104
Total Scores
MCC 0.546
Average MCC ± 95% Confidence Intervals 0.560 ± 0.222
Sensitivity 0.366
Positive Predictive Value 0.822
Nr of predictions 4

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.75 0.57 1.00 17 2833 1 0 0 1 13
3J2L_3 0.45 0.32 0.63 17 7848 11 1 9 1 36
3ZEX_D 0.58 0.39 0.86 19 6999 3 0 3 0 30
4FRG_B 0.47 0.22 1.00 7 3479 0 0 0 0 25

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.