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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of TurboFold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & TurboFold(seed) [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) TurboFold(seed)
MCC 0.461 > 0.458
Average MCC ± 95% Confidence Intervals 0.447 ± 0.309 < 0.467 ± 0.377
Sensitivity 0.323 < 0.383
Positive Predictive Value 0.663 > 0.554
Total TP 65 < 77
Total TN 34536 > 34495
Total FP 45 < 74
Total FP CONTRA 1 < 8
Total FP INCONS 32 < 54
Total FP COMP 12 = 12
Total FN 136 > 124
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and TurboFold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and TurboFold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and TurboFold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and TurboFold(seed)).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 65
Total TN 34536
Total FP 45
Total FP CONTRA 1
Total FP INCONS 32
Total FP COMP 12
Total FN 136
Total Scores
MCC 0.461
Average MCC ± 95% Confidence Intervals 0.447 ± 0.309
Sensitivity 0.323
Positive Predictive Value 0.663
Nr of predictions 6

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.71 0.55 0.92 11 978 1 0 1 0 9
2LC8_A -0.01 0.00 0.00 0 1530 10 0 10 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.60 0.38 0.94 16 3899 1 0 1 0 26
3ZEX_C 0.32 0.19 0.53 10 14177 13 1 8 4 42
4A1C_2 0.31 0.24 0.40 8 11761 20 0 12 8 25

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Performance of TurboFold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 77
Total TN 34495
Total FP 74
Total FP CONTRA 8
Total FP INCONS 54
Total FP COMP 12
Total FN 124
Total Scores
MCC 0.458
Average MCC ± 95% Confidence Intervals 0.467 ± 0.377
Sensitivity 0.383
Positive Predictive Value 0.554
Nr of predictions 6

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.90 0.95 18 971 1 0 1 0 2
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22
3ZEX_C 0.39 0.27 0.56 14 14171 14 2 9 3 38
4A1C_2 0.15 0.15 0.15 5 11748 37 3 25 9 28

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.