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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAalifold(seed) - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAalifold(seed) & CRWrnafold [.zip] - may take several seconds...


Overview

Metric RNAalifold(seed) CRWrnafold
MCC 0.500 > 0.419
Average MCC ± 95% Confidence Intervals 0.467 ± 0.269 > 0.438 ± 0.318
Sensitivity 0.320 < 0.377
Positive Predictive Value 0.789 > 0.475
Total TP 56 < 66
Total TN 24138 > 24070
Total FP 18 < 83
Total FP CONTRA 1 < 12
Total FP INCONS 14 < 61
Total FP COMP 3 < 10
Total FN 119 > 109
P-value 0.0

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Performance plots


  1. Comparison of performance of RNAalifold(seed) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(seed) and CRWrnafold).

  2. Comparison of performance of RNAalifold(seed) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(seed) and CRWrnafold).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(seed) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(seed) and CRWrnafold).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(seed) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(seed) and CRWrnafold).

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Performance of RNAalifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNAalifold(seed)

Total Base Pair Counts
Total TP 56
Total TN 24138
Total FP 18
Total FP CONTRA 1
Total FP INCONS 14
Total FP COMP 3
Total FN 119
Total Scores
MCC 0.500
Average MCC ± 95% Confidence Intervals 0.467 ± 0.269
Sensitivity 0.320
Positive Predictive Value 0.789
Nr of predictions 6

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2. Individual counts for RNAalifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1528 12 0 12 0 20
3SD1_A 0.58 0.40 0.85 17 3896 3 1 2 0 25
4A1C_2 0.39 0.15 1.00 5 11776 2 0 0 2 28
4AOB_A 0.72 0.52 1.00 22 4349 1 0 0 1 20
4ENB_A 0.56 0.32 1.00 6 1269 0 0 0 0 13
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 66
Total TN 24070
Total FP 83
Total FP CONTRA 12
Total FP INCONS 61
Total FP COMP 10
Total FN 109
Total Scores
MCC 0.419
Average MCC ± 95% Confidence Intervals 0.438 ± 0.318
Sensitivity 0.377
Positive Predictive Value 0.475
Nr of predictions 6

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
3SD1_A 0.52 0.45 0.61 19 3885 12 2 10 0 23
4A1C_2 0.13 0.15 0.13 5 11741 44 4 31 9 28
4AOB_A 0.59 0.48 0.74 20 4344 8 2 5 1 22
4ENB_A 0.70 0.58 0.85 11 1262 2 1 1 0 8
4ENC_A 0.70 0.58 0.85 11 1313 2 1 1 0 8

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.