CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of Alterna - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & Alterna [.zip] - may take several seconds...


Overview

Metric TurboFold(20) Alterna
MCC 0.721 > 0.654
Average MCC ± 95% Confidence Intervals 0.745 ± 0.220 > 0.692 ± 0.338
Sensitivity 0.602 > 0.569
Positive Predictive Value 0.871 > 0.761
Total TP 74 > 70
Total TN 10035 > 10028
Total FP 13 < 24
Total FP CONTRA 1 < 2
Total FP INCONS 10 < 20
Total FP COMP 2 = 2
Total FN 49 < 53
P-value 0.0

^top




Performance plots


  1. Comparison of performance of TurboFold(20) and Alterna. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Alterna).

  2. Comparison of performance of TurboFold(20) and Alterna. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Alterna).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Alterna. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Alterna).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Alterna. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Alterna).

^top





Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 74
Total TN 10035
Total FP 13
Total FP CONTRA 1
Total FP INCONS 10
Total FP COMP 2
Total FN 49
Total Scores
MCC 0.721
Average MCC ± 95% Confidence Intervals 0.745 ± 0.220
Sensitivity 0.602
Positive Predictive Value 0.871
Nr of predictions 4

^top



2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.90 0.95 18 971 1 0 1 0 2
3AMU_B 0.70 0.59 0.84 16 2984 5 0 3 2 11
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22

^top



Performance of Alterna - scored lower in this pairwise comparison

1. Total counts & total scores for Alterna

Total Base Pair Counts
Total TP 70
Total TN 10028
Total FP 24
Total FP CONTRA 2
Total FP INCONS 20
Total FP COMP 2
Total FN 53
Total Scores
MCC 0.654
Average MCC ± 95% Confidence Intervals 0.692 ± 0.338
Sensitivity 0.569
Positive Predictive Value 0.761
Nr of predictions 4

^top



2. Individual counts for Alterna [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
3AMU_B 0.64 0.59 0.70 16 2980 9 0 7 2 11
3RKF_A 0.69 0.56 0.86 19 2189 3 1 2 0 15
3SD1_A 0.46 0.38 0.57 16 3888 12 1 11 0 26

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.