CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric TurboFold(20) Carnac(seed)
MCC 0.600 > 0.233
Average MCC ± 95% Confidence Intervals 0.623 ± 0.154 > 0.097 ± 0.220
Sensitivity 0.473 > 0.055
Positive Predictive Value 0.766 < 1.000
Total TP 164 > 19
Total TN 50478 < 50673
Total FP 63 > 0
Total FP CONTRA 5 > 0
Total FP INCONS 45 > 0
Total FP COMP 13 > 0
Total FN 183 < 328
P-value 8.88760648134e-09

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Performance plots


  1. Comparison of performance of TurboFold(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Carnac(seed)).

  2. Comparison of performance of TurboFold(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Carnac(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Carnac(seed)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Carnac(seed)).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 164
Total TN 50478
Total FP 63
Total FP CONTRA 5
Total FP INCONS 45
Total FP COMP 13
Total FN 183
Total Scores
MCC 0.600
Average MCC ± 95% Confidence Intervals 0.623 ± 0.154
Sensitivity 0.473
Positive Predictive Value 0.766
Nr of predictions 10

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.90 0.95 18 971 1 0 1 0 2
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22
3ZEX_C 0.39 0.27 0.56 14 14171 14 2 9 3 38
4A1C_3 0.69 0.57 0.84 31 7103 6 0 6 0 23
4A1C_2 0.18 0.15 0.21 5 11757 28 0 19 9 28
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10
4FRG_B 0.81 0.66 1.00 21 3465 0 0 0 0 11

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 19
Total TN 50673
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 328
Total Scores
MCC 0.233
Average MCC ± 95% Confidence Intervals 0.097 ± 0.220
Sensitivity 0.055
Positive Predictive Value 1.000
Nr of predictions 10

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
3RKF_A 0.00 0.00 0.00 0 2211 0 0 0 0 34
3SD1_A 0.00 0.00 0.00 0 3916 0 0 0 0 42
3ZEX_C 0.00 0.00 0.00 0 14196 0 0 0 0 52
4A1C_3 0.00 0.00 0.00 0 7140 0 0 0 0 54
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19
4FRG_B 0.00 0.00 0.00 0 3486 0 0 0 0 32

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.