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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of Murlet(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & Murlet(seed) [.zip] - may take several seconds...


Overview

Metric TurboFold(20) Murlet(seed)
MCC 0.582 > 0.457
Average MCC ± 95% Confidence Intervals 0.616 ± 0.174 > 0.473 ± 0.108
Sensitivity 0.454 > 0.253
Positive Predictive Value 0.751 < 0.831
Total TP 133 > 74
Total TN 43375 < 43463
Total FP 57 > 16
Total FP CONTRA 5 > 1
Total FP INCONS 39 > 14
Total FP COMP 13 > 1
Total FN 160 < 219
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and Murlet(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Murlet(seed)).

  2. Comparison of performance of TurboFold(20) and Murlet(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Murlet(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Murlet(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Murlet(seed)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Murlet(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Murlet(seed)).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 133
Total TN 43375
Total FP 57
Total FP CONTRA 5
Total FP INCONS 39
Total FP COMP 13
Total FN 160
Total Scores
MCC 0.582
Average MCC ± 95% Confidence Intervals 0.616 ± 0.174
Sensitivity 0.454
Positive Predictive Value 0.751
Nr of predictions 9

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.90 0.95 18 971 1 0 1 0 2
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22
3ZEX_C 0.39 0.27 0.56 14 14171 14 2 9 3 38
4A1C_2 0.18 0.15 0.21 5 11757 28 0 19 9 28
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10
4FRG_B 0.81 0.66 1.00 21 3465 0 0 0 0 11

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Performance of Murlet(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 74
Total TN 43463
Total FP 16
Total FP CONTRA 1
Total FP INCONS 14
Total FP COMP 1
Total FN 219
Total Scores
MCC 0.457
Average MCC ± 95% Confidence Intervals 0.473 ± 0.108
Sensitivity 0.253
Positive Predictive Value 0.831
Nr of predictions 9

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.59 0.40 0.89 8 981 1 0 1 0 12
3RKF_A 0.53 0.35 0.80 12 2196 3 1 2 0 22
3SD1_A 0.47 0.26 0.85 11 3903 2 0 2 0 31
3ZEX_C 0.37 0.13 1.00 7 14189 0 0 0 0 45
4A1C_2 0.46 0.21 1.00 7 11774 0 0 0 0 26
4AOB_A 0.58 0.33 1.00 14 4357 1 0 0 1 28
4ENB_A 0.56 0.32 1.00 6 1269 0 0 0 0 13
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13
4FRG_B 0.15 0.09 0.25 3 3474 9 0 9 0 29

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.