CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of MXScarna(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & MXScarna(20) [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) MXScarna(20)
MCC 0.565 > 0.532
Average MCC ± 95% Confidence Intervals 0.600 ± 0.172 > 0.523 ± 0.164
Sensitivity 0.454 > 0.422
Positive Predictive Value 0.708 > 0.675
Total TP 143 > 133
Total TN 47004 < 47009
Total FP 72 < 83
Total FP CONTRA 8 = 8
Total FP INCONS 51 < 56
Total FP COMP 13 < 19
Total FN 172 < 182
P-value 0.0

^top




Performance plots


  1. Comparison of performance of TurboFold(seed) and MXScarna(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and MXScarna(20)).

  2. Comparison of performance of TurboFold(seed) and MXScarna(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and MXScarna(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and MXScarna(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and MXScarna(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and MXScarna(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and MXScarna(20)).

^top





Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 143
Total TN 47004
Total FP 72
Total FP CONTRA 8
Total FP INCONS 51
Total FP COMP 13
Total FN 172
Total Scores
MCC 0.565
Average MCC ± 95% Confidence Intervals 0.600 ± 0.172
Sensitivity 0.454
Positive Predictive Value 0.708
Nr of predictions 9

^top



2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.90 0.95 18 971 1 0 1 0 2
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22
3ZEX_C 0.39 0.27 0.56 14 14171 14 2 9 3 38
4A1C_3 0.69 0.57 0.84 31 7103 6 0 6 0 23
4A1C_2 0.15 0.15 0.15 5 11748 37 3 25 9 28
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

^top



Performance of MXScarna(20) - scored lower in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 133
Total TN 47009
Total FP 83
Total FP CONTRA 8
Total FP INCONS 56
Total FP COMP 19
Total FN 182
Total Scores
MCC 0.532
Average MCC ± 95% Confidence Intervals 0.523 ± 0.164
Sensitivity 0.422
Positive Predictive Value 0.675
Nr of predictions 9

^top



2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.73 0.70 0.78 14 972 4 0 4 0 6
3RKF_A 0.72 0.53 1.00 18 2193 0 0 0 0 16
3SD1_A 0.63 0.55 0.74 23 3885 8 2 6 0 19
3ZEX_C 0.31 0.21 0.46 11 14172 13 2 11 0 41
4A1C_3 0.64 0.56 0.75 30 7100 11 2 8 1 24
4A1C_2 0.18 0.15 0.21 5 11757 36 2 17 17 28
4AOB_A 0.62 0.55 0.72 23 4339 10 0 9 1 19
4ENB_A 0.26 0.11 0.67 2 1272 1 0 1 0 17
4ENC_A 0.60 0.37 1.00 7 1319 0 0 0 0 12

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.