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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of MaxExpect - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & MaxExpect [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) MaxExpect
MCC 0.544 > 0.506
Average MCC ± 95% Confidence Intervals 0.553 ± 0.185 > 0.507 ± 0.194
Sensitivity 0.439 > 0.418
Positive Predictive Value 0.679 > 0.620
Total TP 163 > 155
Total TN 53657 > 53647
Total FP 90 < 115
Total FP CONTRA 11 < 14
Total FP INCONS 66 < 81
Total FP COMP 13 < 20
Total FN 208 < 216
P-value 1.39551335374e-08

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Performance plots


  1. Comparison of performance of TurboFold(seed) and MaxExpect. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and MaxExpect).

  2. Comparison of performance of TurboFold(seed) and MaxExpect. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and MaxExpect).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and MaxExpect. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and MaxExpect).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and MaxExpect. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and MaxExpect).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 163
Total TN 53657
Total FP 90
Total FP CONTRA 11
Total FP INCONS 66
Total FP COMP 13
Total FN 208
Total Scores
MCC 0.544
Average MCC ± 95% Confidence Intervals 0.553 ± 0.185
Sensitivity 0.439
Positive Predictive Value 0.679
Nr of predictions 11

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.90 0.95 18 971 1 0 1 0 2
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22
3ZEX_C 0.39 0.27 0.56 14 14171 14 2 9 3 38
4A1C_3 0.69 0.57 0.84 31 7103 6 0 6 0 23
4A1C_2 0.15 0.15 0.15 5 11748 37 3 25 9 28
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10
4FRN_A 0.69 0.56 0.87 20 5128 3 1 2 0 16

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Performance of MaxExpect - scored lower in this pairwise comparison

1. Total counts & total scores for MaxExpect

Total Base Pair Counts
Total TP 155
Total TN 53647
Total FP 115
Total FP CONTRA 14
Total FP INCONS 81
Total FP COMP 20
Total FN 216
Total Scores
MCC 0.506
Average MCC ± 95% Confidence Intervals 0.507 ± 0.194
Sensitivity 0.418
Positive Predictive Value 0.620
Nr of predictions 11

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2. Individual counts for MaxExpect [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.58 0.48 0.71 20 3888 8 1 7 0 22
3ZEX_C 0.41 0.27 0.64 14 14174 16 2 6 8 38
4A1C_3 0.69 0.57 0.84 31 7103 6 0 6 0 23
4A1C_2 0.14 0.15 0.14 5 11746 41 4 26 11 28
4AOB_A 0.50 0.40 0.63 17 4344 11 2 8 1 25
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.31 0.26 0.38 5 1313 8 1 7 0 14
4FRN_A 0.45 0.36 0.57 13 5128 10 2 8 0 23

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.