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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of Murlet(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & Murlet(20) [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) Murlet(20)
MCC 0.565 > 0.521
Average MCC ± 95% Confidence Intervals 0.600 ± 0.172 > 0.521 ± 0.138
Sensitivity 0.454 > 0.384
Positive Predictive Value 0.708 < 0.712
Total TP 143 > 121
Total TN 47004 < 47036
Total FP 72 > 57
Total FP CONTRA 8 > 4
Total FP INCONS 51 > 45
Total FP COMP 13 > 8
Total FN 172 < 194
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(seed) and Murlet(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and Murlet(20)).

  2. Comparison of performance of TurboFold(seed) and Murlet(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and Murlet(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and Murlet(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and Murlet(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and Murlet(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and Murlet(20)).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 143
Total TN 47004
Total FP 72
Total FP CONTRA 8
Total FP INCONS 51
Total FP COMP 13
Total FN 172
Total Scores
MCC 0.565
Average MCC ± 95% Confidence Intervals 0.600 ± 0.172
Sensitivity 0.454
Positive Predictive Value 0.708
Nr of predictions 9

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.90 0.95 18 971 1 0 1 0 2
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22
3ZEX_C 0.39 0.27 0.56 14 14171 14 2 9 3 38
4A1C_3 0.69 0.57 0.84 31 7103 6 0 6 0 23
4A1C_2 0.15 0.15 0.15 5 11748 37 3 25 9 28
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of Murlet(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 121
Total TN 47036
Total FP 57
Total FP CONTRA 4
Total FP INCONS 45
Total FP COMP 8
Total FN 194
Total Scores
MCC 0.521
Average MCC ± 95% Confidence Intervals 0.521 ± 0.138
Sensitivity 0.384
Positive Predictive Value 0.712
Nr of predictions 9

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2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.53 0.50 0.59 10 973 7 0 7 0 10
3RKF_A 0.68 0.47 1.00 16 2195 0 0 0 0 18
3SD1_A 0.68 0.57 0.83 24 3887 5 1 4 0 18
3ZEX_C 0.34 0.23 0.50 12 14172 15 1 11 3 40
4A1C_3 0.59 0.41 0.85 22 7114 4 0 4 0 32
4A1C_2 0.17 0.15 0.20 5 11756 24 2 18 4 28
4AOB_A 0.72 0.55 0.96 23 4347 2 0 1 1 19
4ENB_A 0.46 0.21 1.00 4 1271 0 0 0 0 15
4ENC_A 0.51 0.26 1.00 5 1321 0 0 0 0 14

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.