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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CMfinder(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CMfinder(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric CMfinder(20) Carnac(seed)
MCC 0.385 > 0.000
Average MCC ± 95% Confidence Intervals 0.389 ± 0.528 > 0.000 ± 0.000
Sensitivity 0.310 > 0.000
Positive Predictive Value 0.486 > 0.000
Total TP 18 > 0
Total TN 8668 < 8705
Total FP 21 > 0
Total FP CONTRA 8 > 0
Total FP INCONS 11 > 0
Total FP COMP 2 > 0
Total FN 40 < 58
P-value 0.0

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Performance plots


  1. Comparison of performance of CMfinder(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CMfinder(20) and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CMfinder(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CMfinder(20) and Carnac(seed)).

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Performance of CMfinder(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 18
Total TN 8668
Total FP 21
Total FP CONTRA 8
Total FP INCONS 11
Total FP COMP 2
Total FN 40
Total Scores
MCC 0.385
Average MCC ± 95% Confidence Intervals 0.389 ± 0.528
Sensitivity 0.310
Positive Predictive Value 0.486
Nr of predictions 3

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 0
Total TN 8705
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 58
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 3

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3E_8 0.00 0.00 0.00 0 2742 0 0 0 0 15
3J3F_8 0.00 0.00 0.00 0 4761 0 0 0 0 19
4FRG_B 0.00 0.00 0.00 0 1202 0 0 0 0 24

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.