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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CMfinder(20) - scored higher in this pairwise comparison

  4. Performance of Murlet(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for CMfinder(20) & Murlet(20) [.zip] - may take several seconds...


Overview

Metric CMfinder(20) Murlet(20)
MCC 0.580 > 0.522
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352 > 0.514 ± 0.312
Sensitivity 0.500 > 0.490
Positive Predictive Value 0.681 > 0.565
Total TP 49 > 48
Total TN 10820 > 10807
Total FP 26 < 47
Total FP CONTRA 12 > 9
Total FP INCONS 11 < 28
Total FP COMP 3 < 10
Total FN 49 < 50
P-value 0.0

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Performance plots


  1. Comparison of performance of CMfinder(20) and Murlet(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CMfinder(20) and Murlet(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CMfinder(20) and Murlet(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CMfinder(20) and Murlet(20)).

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Performance of CMfinder(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 49
Total TN 10820
Total FP 26
Total FP CONTRA 12
Total FP INCONS 11
Total FP COMP 3
Total FN 49
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352
Sensitivity 0.500
Positive Predictive Value 0.681
Nr of predictions 5

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3D_C 0.81 0.79 0.83 15 950 3 3 0 0 4
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Performance of Murlet(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 48
Total TN 10807
Total FP 47
Total FP CONTRA 9
Total FP INCONS 28
Total FP COMP 10
Total FN 50
Total Scores
MCC 0.522
Average MCC ± 95% Confidence Intervals 0.514 ± 0.312
Sensitivity 0.490
Positive Predictive Value 0.565
Nr of predictions 5

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2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.65 0.62 0.68 13 1200 6 1 5 0 8
3J3D_C 0.84 0.84 0.84 16 949 3 3 0 0 3
3J3E_8 0.35 0.33 0.38 5 2729 13 2 6 5 10
3J3F_8 0.54 0.53 0.56 10 4743 13 2 6 5 9
4FRG_B 0.19 0.17 0.25 4 1186 12 1 11 0 20

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.