CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CMfinder(20) - scored higher in this pairwise comparison

  4. Performance of RNAshapes - scored lower in this pairwise comparison

  5. Compile and download dataset for CMfinder(20) & RNAshapes [.zip] - may take several seconds...


Overview

Metric CMfinder(20) RNAshapes
MCC 0.580 > 0.417
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352 > 0.418 ± 0.187
Sensitivity 0.500 > 0.480
Positive Predictive Value 0.681 > 0.373
Total TP 49 > 47
Total TN 10820 > 10766
Total FP 26 < 109
Total FP CONTRA 12 < 25
Total FP INCONS 11 < 54
Total FP COMP 3 < 30
Total FN 49 < 51
P-value 0.0

^top




Performance plots


  1. Comparison of performance of CMfinder(20) and RNAshapes. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CMfinder(20) and RNAshapes).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CMfinder(20) and RNAshapes. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CMfinder(20) and RNAshapes).

^top





Performance of CMfinder(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 49
Total TN 10820
Total FP 26
Total FP CONTRA 12
Total FP INCONS 11
Total FP COMP 3
Total FN 49
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352
Sensitivity 0.500
Positive Predictive Value 0.681
Nr of predictions 5

^top



2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3D_C 0.81 0.79 0.83 15 950 3 3 0 0 4
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

^top



Performance of RNAshapes - scored lower in this pairwise comparison

1. Total counts & total scores for RNAshapes

Total Base Pair Counts
Total TP 47
Total TN 10766
Total FP 109
Total FP CONTRA 25
Total FP INCONS 54
Total FP COMP 30
Total FN 51
Total Scores
MCC 0.417
Average MCC ± 95% Confidence Intervals 0.418 ± 0.187
Sensitivity 0.480
Positive Predictive Value 0.373
Nr of predictions 5

^top



2. Individual counts for RNAshapes [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.51 0.57 0.48 12 1194 14 3 10 1 9
3J3D_C 0.63 0.68 0.59 13 946 9 3 6 0 6
3J3E_8 0.26 0.33 0.21 5 2718 29 6 13 10 10
3J3F_8 0.33 0.42 0.26 8 4730 42 11 12 19 11
4FRG_B 0.36 0.38 0.38 9 1178 15 2 13 0 15

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.