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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CMfinder(20) - scored higher in this pairwise comparison

  4. Performance of RNAsubopt - scored lower in this pairwise comparison

  5. Compile and download dataset for CMfinder(20) & RNAsubopt [.zip] - may take several seconds...


Overview

Metric CMfinder(20) RNAsubopt
MCC 0.580 > 0.423
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352 > 0.425 ± 0.194
Sensitivity 0.500 = 0.500
Positive Predictive Value 0.681 > 0.368
Total TP 49 = 49
Total TN 10820 > 10759
Total FP 26 < 113
Total FP CONTRA 12 < 29
Total FP INCONS 11 < 55
Total FP COMP 3 < 29
Total FN 49 = 49
P-value 0.0

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Performance plots


  1. Comparison of performance of CMfinder(20) and RNAsubopt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CMfinder(20) and RNAsubopt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CMfinder(20) and RNAsubopt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CMfinder(20) and RNAsubopt).

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Performance of CMfinder(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 49
Total TN 10820
Total FP 26
Total FP CONTRA 12
Total FP INCONS 11
Total FP COMP 3
Total FN 49
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352
Sensitivity 0.500
Positive Predictive Value 0.681
Nr of predictions 5

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3D_C 0.81 0.79 0.83 15 950 3 3 0 0 4
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Performance of RNAsubopt - scored lower in this pairwise comparison

1. Total counts & total scores for RNAsubopt

Total Base Pair Counts
Total TP 49
Total TN 10759
Total FP 113
Total FP CONTRA 29
Total FP INCONS 55
Total FP COMP 29
Total FN 49
Total Scores
MCC 0.423
Average MCC ± 95% Confidence Intervals 0.425 ± 0.194
Sensitivity 0.500
Positive Predictive Value 0.368
Nr of predictions 5

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2. Individual counts for RNAsubopt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.51 0.57 0.48 12 1194 14 2 11 1 9
3J3D_C 0.65 0.74 0.58 14 944 10 5 5 0 5
3J3E_8 0.25 0.33 0.20 5 2717 32 7 13 12 10
3J3F_8 0.35 0.47 0.26 9 4726 42 13 13 16 10
4FRG_B 0.36 0.38 0.38 9 1178 15 2 13 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.