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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CMfinder(20) - scored higher in this pairwise comparison

  4. Performance of RNAwolf - scored lower in this pairwise comparison

  5. Compile and download dataset for CMfinder(20) & RNAwolf [.zip] - may take several seconds...


Overview

Metric CMfinder(20) RNAwolf
MCC 0.580 > 0.452
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352 > 0.455 ± 0.427
Sensitivity 0.500 = 0.500
Positive Predictive Value 0.681 > 0.419
Total TP 49 = 49
Total TN 10820 > 10775
Total FP 26 < 99
Total FP CONTRA 12 < 22
Total FP INCONS 11 < 46
Total FP COMP 3 < 31
Total FN 49 = 49
P-value 0.0

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Performance plots


  1. Comparison of performance of CMfinder(20) and RNAwolf. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CMfinder(20) and RNAwolf).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CMfinder(20) and RNAwolf. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CMfinder(20) and RNAwolf).

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Performance of CMfinder(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 49
Total TN 10820
Total FP 26
Total FP CONTRA 12
Total FP INCONS 11
Total FP COMP 3
Total FN 49
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352
Sensitivity 0.500
Positive Predictive Value 0.681
Nr of predictions 5

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3D_C 0.81 0.79 0.83 15 950 3 3 0 0 4
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Performance of RNAwolf - scored lower in this pairwise comparison

1. Total counts & total scores for RNAwolf

Total Base Pair Counts
Total TP 49
Total TN 10775
Total FP 99
Total FP CONTRA 22
Total FP INCONS 46
Total FP COMP 31
Total FN 49
Total Scores
MCC 0.452
Average MCC ± 95% Confidence Intervals 0.455 ± 0.427
Sensitivity 0.500
Positive Predictive Value 0.419
Nr of predictions 5

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2. Individual counts for RNAwolf [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.54 0.57 0.52 12 1196 12 2 9 1 9
3J3D_C 0.92 0.95 0.90 18 948 3 2 0 1 1
3J3E_8 -0.01 0.00 0.00 0 2719 37 6 17 14 15
3J3F_8 0.28 0.37 0.23 7 4730 39 9 15 15 12
4FRG_B 0.54 0.50 0.60 12 1182 8 3 5 0 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.