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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CMfinder(20) - scored higher in this pairwise comparison

  4. Performance of RSpredict(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CMfinder(20) & RSpredict(seed) [.zip] - may take several seconds...


Overview

Metric CMfinder(20) RSpredict(seed)
MCC 0.580 > 0.047
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352 > 0.033 ± 0.106
Sensitivity 0.500 > 0.020
Positive Predictive Value 0.681 > 0.125
Total TP 49 > 2
Total TN 10820 < 10876
Total FP 26 > 15
Total FP CONTRA 12 > 4
Total FP INCONS 11 > 10
Total FP COMP 3 > 1
Total FN 49 < 96
P-value 0.0

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Performance plots


  1. Comparison of performance of CMfinder(20) and RSpredict(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CMfinder(20) and RSpredict(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CMfinder(20) and RSpredict(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CMfinder(20) and RSpredict(seed)).

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Performance of CMfinder(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 49
Total TN 10820
Total FP 26
Total FP CONTRA 12
Total FP INCONS 11
Total FP COMP 3
Total FN 49
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352
Sensitivity 0.500
Positive Predictive Value 0.681
Nr of predictions 5

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3D_C 0.81 0.79 0.83 15 950 3 3 0 0 4
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Performance of RSpredict(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(seed)

Total Base Pair Counts
Total TP 2
Total TN 10876
Total FP 15
Total FP CONTRA 4
Total FP INCONS 10
Total FP COMP 1
Total FN 96
Total Scores
MCC 0.047
Average MCC ± 95% Confidence Intervals 0.033 ± 0.106
Sensitivity 0.020
Positive Predictive Value 0.125
Nr of predictions 5

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2. Individual counts for RSpredict(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 -0.01 0.00 0.00 0 1215 4 0 4 0 21
3J3D_C -0.01 0.00 0.00 0 964 4 1 3 0 19
3J3E_8 0.00 0.00 0.00 0 2742 0 0 0 0 15
3J3F_8 0.19 0.11 0.33 2 4755 5 3 1 1 17
4FRG_B -0.01 0.00 0.00 0 1200 2 0 2 0 24

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.