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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CMfinder(20) - scored higher in this pairwise comparison

  4. Performance of Vsfold5 - scored lower in this pairwise comparison

  5. Compile and download dataset for CMfinder(20) & Vsfold5 [.zip] - may take several seconds...


Overview

Metric CMfinder(20) Vsfold5
MCC 0.580 > 0.489
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352 > 0.489 ± 0.325
Sensitivity 0.500 < 0.551
Positive Predictive Value 0.681 > 0.443
Total TP 49 < 54
Total TN 10820 > 10770
Total FP 26 < 92
Total FP CONTRA 12 < 32
Total FP INCONS 11 < 36
Total FP COMP 3 < 24
Total FN 49 > 44
P-value 0.0

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Performance plots


  1. Comparison of performance of CMfinder(20) and Vsfold5. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CMfinder(20) and Vsfold5).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CMfinder(20) and Vsfold5. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CMfinder(20) and Vsfold5).

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Performance of CMfinder(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 49
Total TN 10820
Total FP 26
Total FP CONTRA 12
Total FP INCONS 11
Total FP COMP 3
Total FN 49
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352
Sensitivity 0.500
Positive Predictive Value 0.681
Nr of predictions 5

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3D_C 0.81 0.79 0.83 15 950 3 3 0 0 4
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Performance of Vsfold5 - scored lower in this pairwise comparison

1. Total counts & total scores for Vsfold5

Total Base Pair Counts
Total TP 54
Total TN 10770
Total FP 92
Total FP CONTRA 32
Total FP INCONS 36
Total FP COMP 24
Total FN 44
Total Scores
MCC 0.489
Average MCC ± 95% Confidence Intervals 0.489 ± 0.325
Sensitivity 0.551
Positive Predictive Value 0.443
Nr of predictions 5

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2. Individual counts for Vsfold5 [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.76 0.76 0.76 16 1198 6 3 2 1 5
3J3D_C 0.63 0.68 0.59 13 946 9 3 6 0 6
3J3E_8 0.10 0.13 0.08 2 2718 31 10 12 9 13
3J3F_8 0.36 0.47 0.27 9 4728 38 13 11 14 10
4FRG_B 0.60 0.58 0.64 14 1180 8 3 5 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.