CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CRWrnafold - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CRWrnafold & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric CRWrnafold Carnac(seed)
MCC 0.513 > 0.177
Average MCC ± 95% Confidence Intervals 0.533 ± 0.387 > 0.078 ± 0.199
Sensitivity 0.524 > 0.032
Positive Predictive Value 0.516 < 1.000
Total TP 66 > 4
Total TN 8854 < 8978
Total FP 83 > 0
Total FP CONTRA 21 > 0
Total FP INCONS 41 > 0
Total FP COMP 21 > 0
Total FN 60 < 122
P-value 0.0

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Performance plots


  1. Comparison of performance of CRWrnafold and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CRWrnafold and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CRWrnafold and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CRWrnafold and Carnac(seed)).

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Performance of CRWrnafold - scored higher in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 66
Total TN 8854
Total FP 83
Total FP CONTRA 21
Total FP INCONS 41
Total FP COMP 21
Total FN 60
Total Scores
MCC 0.513
Average MCC ± 95% Confidence Intervals 0.533 ± 0.387
Sensitivity 0.524
Positive Predictive Value 0.516
Nr of predictions 6

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3SD1_A 0.63 0.66 0.61 19 1502 12 6 6 0 10
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 4
Total TN 8978
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 122
Total Scores
MCC 0.177
Average MCC ± 95% Confidence Intervals 0.078 ± 0.199
Sensitivity 0.032
Positive Predictive Value 1.000
Nr of predictions 6

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.22 1.00 4 524 0 0 0 0 14
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.