CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(seed) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(seed) CMfinder(20)
MCC 0.615 > 0.580
Average MCC ± 95% Confidence Intervals 0.582 ± 0.194 > 0.564 ± 0.352
Sensitivity 0.418 < 0.500
Positive Predictive Value 0.911 > 0.681
Total TP 41 < 49
Total TN 10847 > 10820
Total FP 7 < 26
Total FP CONTRA 3 < 12
Total FP INCONS 1 < 11
Total FP COMP 3 = 3
Total FN 57 > 49
P-value 0.0

^top




Performance plots


  1. Comparison of performance of CentroidAlifold(seed) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(seed) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(seed) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(seed) and CMfinder(20)).

^top





Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(seed)

Total Base Pair Counts
Total TP 41
Total TN 10847
Total FP 7
Total FP CONTRA 3
Total FP INCONS 1
Total FP COMP 3
Total FN 57
Total Scores
MCC 0.615
Average MCC ± 95% Confidence Intervals 0.582 ± 0.194
Sensitivity 0.418
Positive Predictive Value 0.911
Nr of predictions 5

^top



2. Individual counts for CentroidAlifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.53 0.29 1.00 6 1213 0 0 0 0 15
3J3D_C 0.56 0.32 1.00 6 962 0 0 0 0 13
3J3E_8 0.39 0.20 0.75 3 2738 1 1 0 0 12
3J3F_8 0.62 0.47 0.82 9 4750 4 2 0 2 10
4FRG_B 0.81 0.71 0.94 17 1184 2 0 1 1 7

^top



Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 49
Total TN 10820
Total FP 26
Total FP CONTRA 12
Total FP INCONS 11
Total FP COMP 3
Total FN 49
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352
Sensitivity 0.500
Positive Predictive Value 0.681
Nr of predictions 5

^top



2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3D_C 0.81 0.79 0.83 15 950 3 3 0 0 4
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.