CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & CRWrnafold [.zip] - may take several seconds...


Overview

Metric ContextFold CRWrnafold
MCC 0.662 > 0.473
Average MCC ± 95% Confidence Intervals 0.676 ± 0.208 > 0.493 ± 0.312
Sensitivity 0.608 > 0.485
Positive Predictive Value 0.731 > 0.477
Total TP 79 > 63
Total TN 9028 > 9004
Total FP 44 < 91
Total FP CONTRA 6 < 21
Total FP INCONS 23 < 48
Total FP COMP 15 < 22
Total FN 51 < 67
P-value 0.0

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Performance plots


  1. Comparison of performance of ContextFold and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and CRWrnafold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and CRWrnafold).

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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 79
Total TN 9028
Total FP 44
Total FP CONTRA 6
Total FP INCONS 23
Total FP COMP 15
Total FN 51
Total Scores
MCC 0.662
Average MCC ± 95% Confidence Intervals 0.676 ± 0.208
Sensitivity 0.608
Positive Predictive Value 0.731
Nr of predictions 7

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.58 0.56 0.63 10 512 6 0 6 0 8
3J0L_a - 0.80 0.73 0.89 8 402 2 0 1 1 3
3U4M_B - 0.98 0.95 1.00 21 1255 0 0 0 0 1
4A1C_2 0.26 0.25 0.28 5 4498 26 3 10 13 15
4AOB_A 0.62 0.59 0.68 17 1412 9 2 6 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 63
Total TN 9004
Total FP 91
Total FP CONTRA 21
Total FP INCONS 48
Total FP COMP 22
Total FN 67
Total Scores
MCC 0.473
Average MCC ± 95% Confidence Intervals 0.493 ± 0.312
Sensitivity 0.485
Positive Predictive Value 0.477
Nr of predictions 7

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3J0L_a - 0.39 0.36 0.44 4 402 6 3 2 1 7
3U4M_B - 0.49 0.55 0.46 12 1250 14 3 11 0 10
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.