CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Cylofold - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Cylofold & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric Cylofold RNASampler(seed)
MCC 0.614 > 0.591
Average MCC ± 95% Confidence Intervals 0.630 ± 0.243 > 0.548 ± 0.435
Sensitivity 0.611 > 0.468
Positive Predictive Value 0.626 < 0.756
Total TP 77 > 59
Total TN 9557 < 9602
Total FP 57 > 25
Total FP CONTRA 13 > 5
Total FP INCONS 33 > 14
Total FP COMP 11 > 6
Total FN 49 < 67
P-value 0.0

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Performance plots


  1. Comparison of performance of Cylofold and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Cylofold and RNASampler(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Cylofold and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Cylofold and RNASampler(seed)).

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Performance of Cylofold - scored higher in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 77
Total TN 9557
Total FP 57
Total FP CONTRA 13
Total FP INCONS 33
Total FP COMP 11
Total FN 49
Total Scores
MCC 0.614
Average MCC ± 95% Confidence Intervals 0.630 ± 0.243
Sensitivity 0.611
Positive Predictive Value 0.626
Nr of predictions 5

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2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.64 0.61 0.69 11 512 5 1 4 0 7
3O58_3 0.42 0.50 0.35 11 4733 30 9 11 10 11
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
3W3S_B 0.48 0.45 0.52 15 1960 15 1 13 1 18

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 59
Total TN 9602
Total FP 25
Total FP CONTRA 5
Total FP INCONS 14
Total FP COMP 6
Total FN 67
Total Scores
MCC 0.591
Average MCC ± 95% Confidence Intervals 0.548 ± 0.435
Sensitivity 0.468
Positive Predictive Value 0.756
Nr of predictions 5

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3O58_3 0.54 0.50 0.58 11 4745 13 5 3 5 11
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
3W3S_B 0.60 0.36 1.00 12 1977 1 0 0 1 21

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.