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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric MXScarna(20) CMfinder(20)
MCC 0.657 > 0.580
Average MCC ± 95% Confidence Intervals 0.632 ± 0.372 > 0.564 ± 0.352
Sensitivity 0.653 > 0.500
Positive Predictive Value 0.667 < 0.681
Total TP 64 > 49
Total TN 10796 < 10820
Total FP 54 > 26
Total FP CONTRA 17 > 12
Total FP INCONS 15 > 11
Total FP COMP 22 > 3
Total FN 34 < 49
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and CMfinder(20)).

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Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 64
Total TN 10796
Total FP 54
Total FP CONTRA 17
Total FP INCONS 15
Total FP COMP 22
Total FN 34
Total Scores
MCC 0.657
Average MCC ± 95% Confidence Intervals 0.632 ± 0.372
Sensitivity 0.653
Positive Predictive Value 0.667
Nr of predictions 5

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.93 0.90 0.95 19 1199 1 1 0 0 2
3J3D_C 0.90 0.95 0.86 18 947 3 3 0 0 1
3J3E_8 0.21 0.20 0.23 3 2729 15 4 6 5 12
3J3F_8 0.48 0.53 0.43 10 4738 29 7 6 16 9
4FRG_B 0.65 0.58 0.74 14 1183 6 2 3 1 10

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 49
Total TN 10820
Total FP 26
Total FP CONTRA 12
Total FP INCONS 11
Total FP COMP 3
Total FN 49
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352
Sensitivity 0.500
Positive Predictive Value 0.681
Nr of predictions 5

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3D_C 0.81 0.79 0.83 15 950 3 3 0 0 4
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.