CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric MXScarna(20) Carnac(seed)
MCC 0.659 > 0.000
Average MCC ± 95% Confidence Intervals 0.619 ± 0.124 > 0.000 ± 0.000
Sensitivity 0.619 > 0.000
Positive Predictive Value 0.708 > 0.000
Total TP 250 > 0
Total TN 38234 < 38587
Total FP 169 > 0
Total FP CONTRA 46 > 0
Total FP INCONS 57 > 0
Total FP COMP 66 > 0
Total FN 154 < 404
P-value 1.55268413083e-08

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Performance plots


  1. Comparison of performance of MXScarna(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and Carnac(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for MXScarna(20) and Carnac(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and Carnac(seed)).

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Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 250
Total TN 38234
Total FP 169
Total FP CONTRA 46
Total FP INCONS 57
Total FP COMP 66
Total FN 154
Total Scores
MCC 0.659
Average MCC ± 95% Confidence Intervals 0.619 ± 0.124
Sensitivity 0.619
Positive Predictive Value 0.708
Nr of predictions 16

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3GX2_A 0.81 0.79 0.85 22 1423 6 2 2 2 6
3IVN_B 0.81 0.74 0.89 17 884 2 2 0 0 6
3J3E_8 0.21 0.20 0.23 3 2729 15 4 6 5 12
3J3F_8 0.48 0.53 0.43 10 4738 29 7 6 16 9
3LA5_A 0.87 0.80 0.95 20 933 1 1 0 0 5
3NPB_A 0.77 0.73 0.82 27 2245 9 2 4 3 10
3O58_3 0.62 0.59 0.65 13 4744 18 5 2 11 9
3PDR_A 0.85 0.82 0.89 41 4794 9 2 3 4 9
3RKF_A 0.86 0.75 1.00 18 848 0 0 0 0 6
3SD1_A 0.74 0.76 0.73 22 1503 9 6 2 1 7
3ZEX_C 0.35 0.31 0.41 9 5352 15 3 10 2 20
4A1C_2 0.22 0.25 0.21 5 4492 36 8 11 17 15
4AOB_A 0.68 0.69 0.69 20 1408 13 2 7 4 9
4ENB_A 0.29 0.13 0.67 2 469 1 0 1 0 13
4ENC_A 0.68 0.47 1.00 7 489 0 0 0 0 8
4FRG_B 0.65 0.58 0.74 14 1183 6 2 3 1 10

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 0
Total TN 38587
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 404
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 16

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3GX2_A 0.00 0.00 0.00 0 1449 0 0 0 0 28
3IVN_B 0.00 0.00 0.00 0 903 0 0 0 0 23
3J3E_8 0.00 0.00 0.00 0 2742 0 0 0 0 15
3J3F_8 0.00 0.00 0.00 0 4761 0 0 0 0 19
3LA5_A 0.00 0.00 0.00 0 954 0 0 0 0 25
3NPB_A 0.00 0.00 0.00 0 2278 0 0 0 0 37
3O58_3 0.00 0.00 0.00 0 4764 0 0 0 0 22
3PDR_A 0.00 0.00 0.00 0 4840 0 0 0 0 50
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
3ZEX_C 0.00 0.00 0.00 0 5374 0 0 0 0 29
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15
4FRG_B 0.00 0.00 0.00 0 1202 0 0 0 0 24

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.