CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of Murlet(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & Murlet(20) [.zip] - may take several seconds...


Overview

Metric MXScarna(20) Murlet(20)
MCC 0.678 > 0.625
Average MCC ± 95% Confidence Intervals 0.666 ± 0.105 > 0.627 ± 0.101
Sensitivity 0.640 > 0.530
Positive Predictive Value 0.724 < 0.744
Total TP 372 > 308
Total TN 68015 < 68115
Total FP 216 > 142
Total FP CONTRA 69 > 28
Total FP INCONS 73 < 78
Total FP COMP 74 > 36
Total FN 209 < 273
P-value 5.06544643719e-08

^top




Performance plots


  1. Comparison of performance of MXScarna(20) and Murlet(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and Murlet(20)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for MXScarna(20) and Murlet(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and Murlet(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and Murlet(20)).

^top





Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 372
Total TN 68015
Total FP 216
Total FP CONTRA 69
Total FP INCONS 73
Total FP COMP 74
Total FN 209
Total Scores
MCC 0.678
Average MCC ± 95% Confidence Intervals 0.666 ± 0.105
Sensitivity 0.640
Positive Predictive Value 0.724
Nr of predictions 21

^top



2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3A2K_C 0.74 0.73 0.76 16 1087 6 1 4 1 6
3GX2_A 0.81 0.79 0.85 22 1423 6 2 2 2 6
3IVN_B 0.81 0.74 0.89 17 884 2 2 0 0 6
3IZ4_A 0.58 0.54 0.63 51 25455 35 18 12 5 44
3J20_0 0.93 0.90 0.95 19 1199 1 1 0 0 2
3J3D_C 0.90 0.95 0.86 18 947 3 3 0 0 1
3J3E_8 0.21 0.20 0.23 3 2729 15 4 6 5 12
3J3F_8 0.48 0.53 0.43 10 4738 29 7 6 16 9
3JYV_7 0.95 0.90 1.00 18 1093 2 0 0 2 2
3LA5_A 0.87 0.80 0.95 20 933 1 1 0 0 5
3NPB_A 0.77 0.73 0.82 27 2245 9 2 4 3 10
3O58_3 0.62 0.59 0.65 13 4744 18 5 2 11 9
3PDR_A 0.85 0.82 0.89 41 4794 9 2 3 4 9
3RKF_A 0.86 0.75 1.00 18 848 0 0 0 0 6
3SD1_A 0.74 0.76 0.73 22 1503 9 6 2 1 7
3ZEX_C 0.35 0.31 0.41 9 5352 15 3 10 2 20
4A1C_2 0.22 0.25 0.21 5 4492 36 8 11 17 15
4AOB_A 0.68 0.69 0.69 20 1408 13 2 7 4 9
4ENB_A 0.29 0.13 0.67 2 469 1 0 1 0 13
4ENC_A 0.68 0.47 1.00 7 489 0 0 0 0 8
4FRG_B 0.65 0.58 0.74 14 1183 6 2 3 1 10

^top



Performance of Murlet(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 308
Total TN 68115
Total FP 142
Total FP CONTRA 28
Total FP INCONS 78
Total FP COMP 36
Total FN 273
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.627 ± 0.101
Sensitivity 0.530
Positive Predictive Value 0.744
Nr of predictions 21

^top



2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3A2K_C 0.88 0.86 0.90 19 1087 2 0 2 0 3
3GX2_A 0.73 0.54 1.00 15 1434 1 0 0 1 13
3IVN_B 0.80 0.65 1.00 15 888 0 0 0 0 8
3IZ4_A 0.46 0.33 0.66 31 25489 22 3 13 6 64
3J20_0 0.65 0.62 0.68 13 1200 6 1 5 0 8
3J3D_C 0.84 0.84 0.84 16 949 3 3 0 0 3
3J3E_8 0.35 0.33 0.38 5 2729 13 2 6 5 10
3J3F_8 0.54 0.53 0.56 10 4743 13 2 6 5 9
3JYV_7 0.84 0.80 0.89 16 1093 4 0 2 2 4
3LA5_A 0.80 0.64 1.00 16 938 0 0 0 0 9
3NPB_A 0.65 0.43 1.00 16 2262 2 0 0 2 21
3O58_3 0.37 0.32 0.44 7 4748 13 4 5 4 15
3PDR_A 0.84 0.76 0.93 38 4799 3 1 2 0 12
3RKF_A 0.81 0.67 1.00 16 850 0 0 0 0 8
3SD1_A 0.82 0.83 0.83 24 1504 5 4 1 0 5
3ZEX_C 0.42 0.38 0.48 11 5351 16 2 10 4 18
4A1C_2 0.22 0.25 0.20 5 4491 24 5 15 4 15
4AOB_A 0.87 0.76 1.00 22 1415 3 0 0 3 7
4ENB_A 0.51 0.27 1.00 4 468 0 0 0 0 11
4ENC_A 0.57 0.33 1.00 5 491 0 0 0 0 10
4FRG_B 0.19 0.17 0.25 4 1186 12 1 11 0 20

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.