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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(seed) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(seed) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric MXScarna(seed) CMfinder(20)
MCC 0.555 > 0.517
Average MCC ± 95% Confidence Intervals 0.525 ± 0.441 > 0.503 ± 0.456
Sensitivity 0.506 > 0.430
Positive Predictive Value 0.615 < 0.630
Total TP 40 > 34
Total TN 9859 < 9870
Total FP 44 > 23
Total FP CONTRA 11 > 9
Total FP INCONS 14 > 11
Total FP COMP 19 > 3
Total FN 39 < 45
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(seed) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(seed) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(seed) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(seed) and CMfinder(20)).

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Performance of MXScarna(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(seed)

Total Base Pair Counts
Total TP 40
Total TN 9859
Total FP 44
Total FP CONTRA 11
Total FP INCONS 14
Total FP COMP 19
Total FN 39
Total Scores
MCC 0.555
Average MCC ± 95% Confidence Intervals 0.525 ± 0.441
Sensitivity 0.506
Positive Predictive Value 0.615
Nr of predictions 4

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2. Individual counts for MXScarna(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.90 0.86 0.95 18 1200 1 1 0 0 3
3J3E_8 0.23 0.20 0.27 3 2731 14 3 5 6 12
3J3F_8 0.48 0.47 0.50 9 4743 21 5 4 12 10
4FRG_B 0.49 0.42 0.59 10 1185 8 2 5 1 14

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 34
Total TN 9870
Total FP 23
Total FP CONTRA 9
Total FP INCONS 11
Total FP COMP 3
Total FN 45
Total Scores
MCC 0.517
Average MCC ± 95% Confidence Intervals 0.503 ± 0.456
Sensitivity 0.430
Positive Predictive Value 0.630
Nr of predictions 4

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.