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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(seed) - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(seed) & CRWrnafold [.zip] - may take several seconds...


Overview

Metric MXScarna(seed) CRWrnafold
MCC 0.544 > 0.513
Average MCC ± 95% Confidence Intervals 0.481 ± 0.289 < 0.533 ± 0.387
Sensitivity 0.492 < 0.524
Positive Predictive Value 0.614 > 0.516
Total TP 62 < 66
Total TN 8881 > 8854
Total FP 57 < 83
Total FP CONTRA 11 < 21
Total FP INCONS 28 < 41
Total FP COMP 18 < 21
Total FN 64 > 60
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(seed) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(seed) and CRWrnafold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(seed) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(seed) and CRWrnafold).

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Performance of MXScarna(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(seed)

Total Base Pair Counts
Total TP 62
Total TN 8881
Total FP 57
Total FP CONTRA 11
Total FP INCONS 28
Total FP COMP 18
Total FN 64
Total Scores
MCC 0.544
Average MCC ± 95% Confidence Intervals 0.481 ± 0.289
Sensitivity 0.492
Positive Predictive Value 0.614
Nr of predictions 6

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2. Individual counts for MXScarna(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 12 0 10 2 18
3SD1_A 0.74 0.76 0.73 22 1503 9 4 4 1 7
4A1C_2 0.45 0.40 0.50 8 4500 20 4 4 12 12
4AOB_A 0.71 0.69 0.74 20 1410 10 2 5 3 9
4ENB_A 0.54 0.40 0.75 6 464 2 0 2 0 9
4ENC_A 0.48 0.40 0.60 6 486 4 1 3 0 9

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 66
Total TN 8854
Total FP 83
Total FP CONTRA 21
Total FP INCONS 41
Total FP COMP 21
Total FN 60
Total Scores
MCC 0.513
Average MCC ± 95% Confidence Intervals 0.533 ± 0.387
Sensitivity 0.524
Positive Predictive Value 0.516
Nr of predictions 6

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3SD1_A 0.63 0.66 0.61 19 1502 12 6 6 0 10
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.