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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Mastr(20) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Mastr(20) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric Mastr(20) CMfinder(20)
MCC 0.590 > 0.580
Average MCC ± 95% Confidence Intervals 0.370 ± 0.630 < 0.564 ± 0.352
Sensitivity 0.388 < 0.500
Positive Predictive Value 0.905 > 0.681
Total TP 38 < 49
Total TN 10850 > 10820
Total FP 5 < 26
Total FP CONTRA 4 < 12
Total FP INCONS 0 < 11
Total FP COMP 1 < 3
Total FN 60 > 49
P-value 0.0

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Performance plots


  1. Comparison of performance of Mastr(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Mastr(20) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Mastr(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Mastr(20) and CMfinder(20)).

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Performance of Mastr(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 38
Total TN 10850
Total FP 5
Total FP CONTRA 4
Total FP INCONS 0
Total FP COMP 1
Total FN 60
Total Scores
MCC 0.590
Average MCC ± 95% Confidence Intervals 0.370 ± 0.630
Sensitivity 0.388
Positive Predictive Value 0.905
Nr of predictions 5

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.95 0.95 0.95 20 1198 2 1 0 1 1
3J3D_C 0.90 0.95 0.86 18 947 3 3 0 0 1
3J3E_8 0.00 0.00 0.00 0 2742 0 0 0 0 15
3J3F_8 0.00 0.00 0.00 0 4761 0 0 0 0 19
4FRG_B 0.00 0.00 0.00 0 1202 0 0 0 0 24

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 49
Total TN 10820
Total FP 26
Total FP CONTRA 12
Total FP INCONS 11
Total FP COMP 3
Total FN 49
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.564 ± 0.352
Sensitivity 0.500
Positive Predictive Value 0.681
Nr of predictions 5

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J3D_C 0.81 0.79 0.83 15 950 3 3 0 0 4
3J3E_8 0.14 0.13 0.17 2 2730 10 3 7 0 13
3J3F_8 0.48 0.47 0.50 9 4743 11 5 4 2 10
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.